Protein Alignment RfC3 and RFC5

DIOPT Version :10

• Sequence 1: NP_609399.1
• Gene: RfC3 / 34423
• FlyBaseID: FBgn0032244
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_031396.1
• Gene: RFC5 / 5985
• HGNCID: 9973
• Length: 340
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 204/339 - (60%)
• Similarity: 256/339 - (75%)
• Gaps: 11/339 - (3%)

  Fly     3 ETSG------PAV----RMPWVEKYRPSGLDDLISHEEIISTITRFISRKQLPHLLFYGPPGTGK 57
            |||.      ||.    .:||||||||..|:|||||::|:|||.:||:..:|||||.||||||||
Human     2 ETSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGK 66

  Fly    58 TSTILACARQLYSPQQFKSMVLELNASDDRGIGIVRGQILNFASTRTIFCDTFKLIILDEADAMT 122
            ||||||||:|||..::|.||||||||||||||.|:||.||:||||||||...|||:|||||||||
Human    67 TSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMT 131

  Fly   123 NDAQNALRRIIEKYTDNVRFCVICNYLSKIIPALQSRCTRFRFAPLSQDQMMPRLEKIIEAEAVQ 187
            .||||||||:|||:|:|.|||:|||||||||||||||||||||.||:.:.|:||||.::|.|.|.
Human   132 QDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVD 196

  Fly   188 ITEDGKRALLTLAKGDMRKVLNVLQSTVMAFDTVNEDNVYMCVGYPLRQDIEQILKALLSGSSLE 252
            |:|||.:||:||:.||||:.||:||||.|||..|.|:.||.|.|:||:.||..||..:|: ....
Human   197 ISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLN-QDFT 260

  Fly   253 DSFKTVESAKYARGLALEDIITELHLFVMRLELPMSVMNKLIVKLAQIEERLAKGCTEVAQTAAL 317
            .:::.:...|..:||||.||:||:||||.|::.|.||...|:.|:|.||.||:.|..|..|.::|
Human   261 TAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL 325

  Fly   318 VAAFFICRDMVSME 331
            :|||.:.||::..|
Human   326 IAAFQVTRDLIVAE 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RfC3	NP_609399.1	rfc	12..321	CDD:234763	194/308 (63%)
RFC5	NP_031396.1	rfc	16..329	CDD:234763	194/313 (62%)