DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RfC3 and rfc4

DIOPT Version :9

Sequence 1:	NP_609399.1	Gene:	RfC3 / 34423	FlyBaseID:	FBgn0032244	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_999902.2	Gene:	rfc4 / 406435	ZFINID:	ZDB-GENE-040824-3	Length:	358	Species:	Danio rerio

Alignment Length:	331	Identity:	128/331 - (38%)
Similarity:	196/331 - (59%)	Gaps:	20/331 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SETSGPAVR---MPWVEKYRPSGLDDLISHEEIISTITRFISRKQLPHLLFYGPPGTGKTSTILA 63
            |.:||...:   :||||||||..:|::...||:::.:.:.:....||:|||||||||||||||||
Zfish    21 SSSSGGEKKQRAVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILA 85

  Fly    64 CARQLYSPQQFKSMVLELNASDDRGIGIVRGQILNFASTRTI-------FCDTFKLIILDEADAM 121
            .||:||.|..::..||||||||:|||.:||.::..||.....       .|..||:|||||||:|
Zfish    86 AARELYGPDLYRQRVLELNASDERGIQVVREKVKRFAQLTVAGTRPDGKTCPPFKIIILDEADSM 150

  Fly   122 TNDAQNALRRIIEKYTDNVRFCVICNYLSKIIPALQSRCTRFRFAPLSQDQMMPRLEKIIEAEAV 186
            |:.||.||||.:||.:...|||:||||:|:||..|.|||::|||.||:.|....|:.:|...|.:
Zfish   151 TSAAQAALRRTMEKESRTTRFCLICNYVSRIIEPLTSRCSKFRFKPLANDVQQERILEICRKENL 215

  Fly   187 QITEDGKRALLTLAKGDMRKVLNVLQS--TVMAFDTVNEDNVYMCVGYPLRQDIEQILKALLSGS 249
            :.|.:|..||:.:::||:||.:..|||  .:.:...:.|..:....|....:.|:.:|.....|
Zfish   216 KYTTEGVDALVRVSEGDLRKAITFLQSGARLNSEREITEQTIIEIAGVVPPKVIQSLLHICYKG- 279

  Fly   250 SLEDSFKTVESA---KYARGLALEDIITELHLFVMRLELPMSVMNKLIVKLAQIEERLAKGCTEV 311
                :|:.:|.|   ...:|.|..:::.:||..::..:|.....:.:..|:|::::.||.|..|.
Zfish   280 ----TFEKLEVAVKDMIDQGYAATNLLNQLHDVIIEEQLSDKQKSVITEKMAEVDKCLADGADEY 340

  Fly   312 AQTAAL 317
            .|..:|
Zfish   341 LQLLSL 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RfC3	NP_609399.1	rfc	12..321	CDD:234763	125/318 (39%)
rfc4	NP_999902.2	rfc	34..346	CDD:234763	124/316 (39%)
		AAA	50..196	CDD:99707	78/145 (54%)
		AAA_assoc_2	212..>262	CDD:292811	13/49 (27%)
		Rep_fac_C	281..348	CDD:285713	16/66 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53599
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000505
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920