DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RfC3 and Rfc5

DIOPT Version :9

Sequence 1:	NP_609399.1	Gene:	RfC3 / 34423	FlyBaseID:	FBgn0032244	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001100616.1	Gene:	Rfc5 / 304528	RGDID:	1309280	Length:	338	Species:	Rattus norvegicus

Alignment Length:	324	Identity:	202/324 - (62%)
Similarity:	252/324 - (77%)	Gaps:	1/324 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 AVRMPWVEKYRPSGLDDLISHEEIISTITRFISRKQLPHLLFYGPPGTGKTSTILACARQLYSPQ 72
            |..:||||||||..|.|||||::|:|||.:|||..:|||||.||||||||||||||||:|||..:
  Rat    15 ARNLPWVEKYRPQTLADLISHQDILSTIQKFISEDRLPHLLLYGPPGTGKTSTILACAKQLYKDK 79

  Fly    73 QFKSMVLELNASDDRGIGIVRGQILNFASTRTIFCDTFKLIILDEADAMTNDAQNALRRIIEKYT 137
            :|.||||||||||||||.||||.||:||||||||...|||:|||||||||.||||||||:|||:|
  Rat    80 EFGSMVLELNASDDRGIDIVRGPILSFASTRTIFKRGFKLVILDEADAMTQDAQNALRRVIEKFT 144

  Fly   138 DNVRFCVICNYLSKIIPALQSRCTRFRFAPLSQDQMMPRLEKIIEAEAVQITEDGKRALLTLAKG 202
            :|.|||:|||||||||||||||||||||.||:.:.|:||||.:::.|.|.|:|||.:||:||:.|
  Rat   145 ENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVQEENVDISEDGMKALVTLSSG 209

  Fly   203 DMRKVLNVLQSTVMAFDTVNEDNVYMCVGYPLRQDIEQILKALLSGSSLEDSFKTVESAKYARGL 267
            |||:.||:||||.|||..|.|:.||.|.|:||:.||..||..:|: .....::|.:...|..:||
  Rat   210 DMRRALNILQSTNMAFGKVTEETVYTCTGHPLKTDIANILDWMLN-QDFTTAYKNIMELKTLKGL 273

  Fly   268 ALEDIITELHLFVMRLELPMSVMNKLIVKLAQIEERLAKGCTEVAQTAALVAAFFICRDMVSME 331
            ||.||:||:||||.|::.|.||...|:.|:|.||.||:.|.:|..|.::|:|||.:.||::..|
  Rat   274 ALHDILTEVHLFVHRVDFPSSVRMHLLTKMADIEYRLSVGTSEKIQLSSLIAAFQVTRDLIVAE 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RfC3	NP_609399.1	rfc	12..321	CDD:234763	196/308 (64%)
Rfc5	NP_001100616.1	rfc	16..327	CDD:234763	196/311 (63%)
		AAA	33..174	CDD:99707	112/140 (80%)
		AAA_assoc_2	190..>218	CDD:292811	16/27 (59%)
		Rep_fac_C	256..325	CDD:285713	29/68 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340633
Domainoid	1	1.000	198	1.000	Domainoid score	I2983
eggNOG	1	0.900	-	-		E1_COG0470
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6730
Inparanoid	1	1.050	403	1.000	Inparanoid score	I1856
OMA	1	1.010	-	-		QHG53599
OrthoDB	1	1.010	-	-		D1071197at2759
OrthoFinder	1	1.000	-	-		FOG0000505
OrthoInspector	1	1.000	-	-		oto97914
orthoMCL	1	0.900	-	-		OOG6_100321
Panther	1	1.100	-	-	LDO	PTHR11669
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3552
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770