Protein Alignment RfC3 and Rad17

DIOPT Version :10

• Sequence 1: NP_609399.1
• Gene: RfC3 / 34423
• FlyBaseID: FBgn0032244
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_035363.2
• Gene: Rad17 / 19356
• MGIID: 1333807
• Length: 688
• Species: Mus musculus
• Alignment Length: 264
• Identity: 62/264 - (23%)
• Similarity: 103/264 - (39%)
• Gaps: 75/264 - (28%)

  Fly    12 PWVEKYRPSGLDDLISHEEIISTITRFISRKQL---PH-----LLFYGPPGTGKTSTILACARQL 68
            |||:||:|....:|..|::.|..:..::..:.|   |.     ||..||||.|||:||...:::|
Mouse    89 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLEVKPKQGGSVLLITGPPGCGKTTTIKILSKEL 153

  Fly    69 --------------YSPQQFKSMV-LELNASDDRGIGIVRGQILNFASTRTIFCDTF-------- 110
                          :....:|.:: ||.|.|           ::.:.|...:|.|..
Mouse   154 GIQVQEWVNPILPDFQKDDYKELLSLESNFS-----------VVPYQSQIAVFNDFLLRATKYSK 207

  Fly   111 ------------KLIILDEADAMTNDAQNALRRIIEKYTDNVRFCVICNYLSKIIPA-------- 155
                        |:|:::|.........|||..|:.|:....| |.:...:|..:..
Mouse   208 LQMLGDDLTTDKKIILVEELPNQFYRDPNALHEILRKHVQIGR-CPLVFIVSDSVSGDNNQRLLF 271

  Fly   156 ---LQSRC--TRFRFAPLSQDQMMPRLEKIIEAEA----VQITEDGKRALLTLAK---GDMRKVL 208
               :|..|  :...|.|::...||..|.:|:..||    .:|....|.:|..|.:   ||:|..:
Mouse   272 PRNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKIIVPNKTSLELLCQGCSGDIRSAI 336

  Fly   209 NVLQ 212
            |.||
Mouse   337 NSLQ 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RfC3	NP_609399.1	rfc	12..321	CDD:234763	62/264 (23%)
Rad17	NP_035363.2	rad24	13..653	CDD:129690	62/264 (23%)
		RAD1-binding motif. /evidence=ECO:0000250|UniProtKB:O75943	17..25
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..84
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	342..379
		Interaction with MCM7. /evidence=ECO:0000250|UniProtKB:O75943	431..688
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	605..688