Protein Alignment Klp31E and si:dkey-26i13.8

DIOPT Version :10

• Sequence 1: NP_609398.2
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Sequence 2: XP_009304780.1
• Gene: si:dkey-26i13.8 / 797363
• ZFINID: ZDB-GENE-090312-134
• Length: 991
• Species: Danio rerio
• Alignment Length: 1072
• Identity: 273/1072 - (25%)
• Similarity: 445/1072 - (41%)
• Gaps: 252/1072 - (23%)

  Fly    11 DSSVRVAVRIRPQNSRELIDMCRICT------TVTLGEP--------QIFLGSDKAFTFDYVFDT 61
            |..:.||:||||.|..|:.:...|..      .|.|.:|        :.....:|.:.||..||.
Zfish    10 DHQLTVALRIRPLNEAEIEEGATIVAHKIDNQMVVLMDPCEDSDNVLRAHRSREKTYMFDLAFDY 74

  Fly    62 NSNQCDIYSDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESSDSVQLGIIPRAVR 126
            .:.|.|:|....:.|:|..:.||||||.|||.||:|||:|| .|.|.|.        ||..|.:.
Zfish    75 TATQEDVYVATTKNLIDGVIAGYNATVFAYGPTGAGKTHTM-LGLDSEP--------GIYIRTLN 130

  Fly   127 HIFSGIEQLEGSSTSEHPAAGGSPQFSLAVQYIELYNEDIFDLLDPFNKNSNFKIHEDASGQITI 191
            .:|..||    .||.:...       |:.:.|||:|||.|.|||:|  .:...::.||..|:|.|
Zfish   131 DLFRAIE----DSTEDLDC-------SVYMSYIEIYNEMIRDLLNP--SSGYLELREDGKGEIRI 182

  Fly   192 SGASIKPIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLLTPSDNVPDNDLE 256
            :|.:........:.:..|.:|...||..||..|..||||||:..:.|:::      ..|.|.:.|
Zfish   183 AGITEFSTCNAKEIMALLTKGNKQRTQESTAANKTSSRSHAILQVTVKQK------SRVKDINEE 241

  Fly   257 TLTSKFHFVDLAGSERLKRTQATGERAREGISINCGLLALGNCISALGDK-SKRALHVPYRDSKL 320
            ....|...|||||:||..:||..|:|.:||..||..||||.|||:||.:| .|.|..|.||||||
Zfish   242 VRVGKLFMVDLAGTERASQTQNRGKRMKEGAHINRSLLALANCINALSEKGGKGAQFVNYRDSKL 306

  Fly   321 TRLLQDSLGGNSQTLMIACVSPSDRDFMETLNTLKYANRARNIKNKVKIN-------QDQSSRTI 378
            ||||:|:|||||:|:||..:||:..:|.|:.|||.||::|:||:.|||.|       ..|.:|.|
Zfish   307 TRLLKDALGGNSRTVMITHISPASSNFEESRNTLVYADKAKNIRTKVKRNLMNVSYHLAQYTRII 371

  Fly   379 SQLRREIAAL----------------------QLELLEYKQGKLIVDCEGNTTISDTFNENKLLL 421
            :.||.||..|                      |.|:.:|..|::.:..|   .:...|.|.
Zfish   372 ADLRSEIERLRAKIDQQSQDQLKGEKADIRNIQAEVQQYSHGEMALLQE---QLLSAFREQ---- 429

  Fly   422 SEIKRLQQRLKSLQSTIATLTQRNADLKTNLDLNKWTSDDNSDVEIAKVVGQYMLEIEEL--QTK 484
            .||:|....|::....:...|.|:.     |.::.|..|.          .:...|.:||  |.|
Zfish   430 MEIRRSLMELENCNMELHIDTSRHL-----LTISDWERDR----------ARARREKDELSGQKK 479

  Fly   485 LIESEEHRKQM--EIKATTSPRNAKPVYDSDIITKAKKDLEREREL--------LMSRSLPGIQN 539
            ..:.||.::.|  |.:..|:.|..    ...::.:.:|.:|.:|||        |.|..:..:..
Zfish   480 HTDKEEEQESMPEEPQYVTAAREE----IGPLLAEQRKTMELKRELEEKLLNMKLKSSKIEELLP 540

  Fly   540 QNVS-SEETEVASSDSEAEEVVKDLEAIDNDIEMRTKLIEQLELTNSRYEQMRTHYEEKLSVLYC 603
            :.:| :|:.::.....:..|:..:...|.:.:..:..::...:....|:||.||         .|
Zfish   541 KRISNTEQRDILMLLCKVHELELEKTEIQSAVLCKENVLRTKDFIIQRHEQQRT---------LC 596

  Fly   604 KIENTQKERDDVLANMTTSVSTPS---KDSLKKVKTDYESKISHMQTEIRKLQNAQREHIRSKQQ 665
                     ||::......:....   .:.|:::.:.|..::|  ...|.::.|.   |..:...
Zfish   597 ---------DDIIHQQKMLIEDQGLCVPEGLQELYSLYFGELS--DGIIDQILNL---HTFTTNN 647

  Fly   666 LKSHEVRIGTLRN-------ELNELKFAKV-KLMKKMSQQSNRHKQEESRKSKEIAQLLKEQRRQ 722
            |.:.::|:..:.|       |.:.:||:.: |..:..|.....:..:.:|..|.::::...::..
Zfish   648 LNARQLRLDVISNLEEADKAEQSNVKFSPLDKHPRDSSSSGLDYDSDTNRVFKSLSKIKPRRQHH 712

  Fly   723 KNAVLTLEAKVSA------------------KEQILKRKTEEVIALRKSQR--GKS--------- 758
            .::..||..||.|                  :|.:...|:..|||.::..|  .||
Zfish   713 SSSSQTLMRKVCAVKDSTPICPTESVSPDTLREIVSDTKSISVIAAKRRSRLQAKSNSRMAGMGL 777

  Fly   759 --GQRAPAHLTSKIATL-------------DGFSTRSARHRWENLYRNIL-----HAARNRQLIT 803
              |.::...:.|.::||             .|.|::|.:.......|..|     |..|:|
Zfish   778 AAGLKSSVSMDSLVSTLPDESAEVRRSHQRHGGSSQSKQDPKRTEGRTELPEKQQHKKRSR---- 838

  Fly   804 QLEKELERLILEREDLSR---------------ELNIME--NGQTADRQTDEFNEVDNLKTNISY 851
            ..|....::...|::.||               .|||::  ||..|:..|.   .|..:|..:|:
Zfish   839 SFEASKRQVQKPRQNASRYPALESISDNHLVRPALNIIQPLNGGPANPATP---PVAKVKIPVSH 900

  Fly   852 IQENIEHVQQAIMEFEDTKDTVQSHVNKIQSLLDEVSTVAEAKFILQKFSDTAIVMSCNLAIAES 916
            ....::..:   :|...|..:.                      |.||.|||....:
Zfish   901 FTGEVQFQK---LEIRGTPPST----------------------IHQKHSDTKRAQA-------- 932

  Fly   917 HLQEKESLLKEVKQESGIQQQILQHFLSQNSN 948
             :.:::....:|...|.:.||...:..|.|.|
Zfish   933 -VYKRQRGQGDVCYPSSLLQQAGNYKKSTNEN 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp31E	NP_609398.2	KISc_KIF4	12..364	CDD:276823	143/366 (39%)
		Mplasa_alph_rch	<372..>748	CDD:275316	77/439 (18%)
		SMC_prok_B	622..>899	CDD:274008	58/353 (16%)
		Rcc_KIF21	798..870	CDD:410202	16/88 (18%)
si:dkey-26i13.8	XP_009304780.1	KISc_KIP3_like	12..349	CDD:276821	142/364 (39%)