Protein Alignment Klp31E and Kif3C

DIOPT Version :10

• Sequence 1: NP_609398.2
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Sequence 2: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 731
• Identity: 224/731 - (30%)
• Similarity: 334/731 - (45%)
• Gaps: 182/731 - (24%)

  Fly    13 SVRVAVRIRPQNSRE-------LIDMCRICTTVTLGEPQIFLGSDKAFTFDYVFDTNSNQCDIYS 70
            :::|.||.||.|..|       ::::.....:||  .|...:...|.|.||.|::..::...||.
  Fly     4 NIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVT--NPSARISQQKKFIFDSVYNMKTDTEVIYD 66

  Fly    71 DCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESSDSVQLGIIPRAVRHIFSGIEQL 135
            :....||:||:.|||.|:.||||||.|||:||      :.:.:.|...||||:...|||..|
  Fly    67 EMCYSLVESTIEGYNGTIFAYGQTGCGKTHTM------QGDENFSNSTGIIPKCFDHIFERI--- 122

  Fly   136 EGSSTSEHPAAGGSPQFSLAVQYIELYNEDIFDLLDPFNKNSNFKIHEDASGQITISGASI---- 196
              |.|:       :.::...|.|:|:|||.|.|||   |||.|..:......::...|.|:
  Fly   123 --SMTT-------NVRYLALVTYLEIYNERIRDLL---NKNENTNVINHFLKELPGIGVSVPTLT 175

  Fly   197 -KPIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLLTPSDNVPDNDL--ETL 258
             :|:...:....:|..|...|.||:|.||..|||||.:|||.:.:    :|..|...:|.  ...
  Fly   176 TQPVVNANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQ----SPFLNSIGSDAFGGIC 236

  Fly   259 TSKFHFVDLAGSERLKRTQATGERAREGISINCGLLALGNCISALGDKSKRALHVPYRDSKLTRL 323
            ..|...||||||||.::|.|.|:|.:|...||..|.||||.||:|.|  .:|.|||:||||||||
  Fly   237 RGKLSLVDLAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVD--GKAKHVPFRDSKLTRL 299

  Fly   324 LQDSLGGNSQTLMIACVSPSDRDFMETLNTLKYANRARNIKNKVKINQDQSSRTISQLRREIAAL 388
            ||||||||::||||:|:||:|..:.||::||:||:||:||.||.|||:|.....:.|.:.||..|
  Fly   300 LQDSLGGNTKTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYL 364

  Fly   389 QLELLEYKQGKLIVDCEGNTTISDTFNENKLLLSEIKRLQQ-RLKSLQSTIATLTQRN--ADLKT 450
            :..|.|.:|           .|:...:.||::.|.:|.:|. .:.|.::.......||  |..||
  Fly   365 KRMLQESQQ-----------IINKNNDPNKIIKSPLKIIQHTNMNSTKNVQIIDLGRNCKASFKT 418

  Fly   451 NLDLNKWTSDDNSDVEIAKVVGQYMLEIEELQTK----LIESEEHRKQMEIKATTSPRNAKPVYD 511
            |          ||                 :.||    ||:|:|   :::::|
  Fly   419 N----------NS-----------------ILTKPNFPLIQSKE---EVQLQA------------ 441

  Fly   512 SDIITKAKKDLERERELLMSRSLPGIQNQNVSSEETEVASSDSEAEEVVKDLEAIDNDIEMRTKL 576
                        |.|..|:.|||.|                   .|.:        :|.|::.|.
  Fly   442 ------------RSRIDLIKRSLIG-------------------GERI--------HDFELKEKH 467

  Fly   577 IEQLELTNSRYEQMRTHYEEKLSVLYCKIENTQKERDDVL----ANMTTSVSTPSKDSLKKVKTD 637
            :.:      :|...|     .||.:...:...:.|..|:|    |.:|..:.         :|.|
  Fly   468 MAR------KYAAQR-----HLSAIAIALSRVKCEDRDLLQGHYATITQEID---------IKND 512

  Fly   638 Y----ESKISHMQTEIRKLQNAQREHIRSKQQLKSHEVRIGTLRNELNELKFAKVKLMKKMSQQS 698
            |    :.||..::.|:..|        .|:.|| ..|..:..:||...::||.: :|..|.|  |
  Fly   513 YIRKCKEKIKMLEMEVSDL--------NSEFQL-DREDYLDEIRNLGRQVKFHQ-QLFLKFS--S 565

  Fly   699 NRHKQEESRKSKEIAQ 714
            |..|.:.:.....|.|
  Fly   566 NPGKFDRNWTPDTILQ 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp31E	NP_609398.2	KISc_KIF4	12..364	CDD:276823	145/364 (40%)
		Mplasa_alph_rch	<372..>748	CDD:275316	73/358 (20%)
		SMC_prok_B	622..>899	CDD:274008	23/97 (24%)
		Rcc_KIF21	798..870	CDD:410202
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	144/363 (40%)