Protein Alignment Klp31E and pav

DIOPT Version :9

• Sequence 1: NP_001162935.1
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Sequence 2: NP_477025.1
• Gene: pav / 38515
• FlyBaseID: FBgn0011692
• Length: 887
• Species: Drosophila melanogaster
• Alignment Length: 1062
• Identity: 254/1062 - (23%)
• Similarity: 401/1062 - (37%)
• Gaps: 338/1062 - (31%)

  Fly     5 VDSINKDSS------VRVAVRIRPQNSRELIDMCRI--CTTVTLGEPQIFLGSDK---------A 52
            |:...:|:|      |.|..|:||..|...:...|:  .||:.|......|...|         .
  Fly    22 VEKQRRDTSDKARDPVNVFCRVRPLQSDADLTSLRVKNSTTIALNPQDQLLQHHKPHNGAQREVQ 86

  Fly    53 FTFDYVFDTNSNQCDIYSDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESSDSVQ 117
            :.|.:||..::.|.|:|:...:.||::.|.|.|:.:..||.|||||||||.....|.
  Fly    87 YIFKHVFQPDATQQDVYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGNLRHR-------- 143

  Fly   118 LGIIPRAVRHIFSGI------------EQLEG-SSTSEHPAA-----------GGSPQF------ 152
             ||:||.:..:|..|            ::|.| ...||..|.           .||.:|
  Fly   144 -GIMPRCLDVLFRTISDYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKD 207

  Fly   153 -------------------------SLAVQYIELYNEDIFDLLDP--FNKNSNFK-IHEDASGQI 189
                                     |:.|.|||:||..::|||:.  ..|....| |.|||:..:
  Fly   208 SDPEIASQASVEPIPLLGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKTLQSKIIREDANRHM 272

  Fly   190 TISGASIKPIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLL-TPSDNVPDN 253
            .:.|.:...:....|||:..|.|...:....|.:|.:|||||::|.|     ||: .|:|:..:|
  Fly   273 FVHGVTEVEVKTVEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNI-----RLVQAPTDSQGEN 332

  Fly   254 ---DLETLT-SKFHFVDLAGSERLKRTQATGERAREGISINCGLLALGNCISALGDKSKRALH-- 312
               |.:.:| |:...||||||||..||:.||.|.||..:||..|:.|..|:..|.:....|.:
  Fly   333 VVQDRQNITVSQLSLVDLAGSERSSRTKNTGVRLREAGNINNSLMTLRTCLEYLRENQLAASNGL 397

  Fly   313 ----VPYRDSKLTRLLQDSLGGNSQTLMIACVSPSDRDFMETLNTLKYANRARNIKNKVKINQDQ 373
                |||||||:|.:.::...|..|..||.|::|...|:.|.:..:|:|...:.:         |
  Fly   398 APKKVPYRDSKITHMFKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFAEMTQEV---------Q 453

  Fly   374 SSRTISQLRREIAALQLELLEYKQGKLIVDCEGNTTISDTFNENKLLLSEIKRLQQRLKSLQSTI 438
            .:|. :.:::::..........|..|:.|:           |.|:|.:.|.|
  Fly   454 IARA-TPMKQDLGLTPGRRKANKLFKIAVN-----------NLNELGIPEAK------------- 493

  Fly   439 ATLTQRNADLKTNLDLNKWTSDDNSDVEIAKVVGQYMLEIEELQTKLIESEEHRKQMEIKATTSP 503
                    ||:.::.|......|....|:.....|  ::|.||...|.:..|.||::
  Fly   494 --------DLEVDVGLVYSLGPDFPAYEMDSPEAQ--IKIRELMHYLEQRIEKRKKL-------- 540

  Fly   504 RNAKPVYDSDIITKAKKDLERE--RELLMSRSLPGIQNQNVSSEETEVASSDSEAEEVVKDLEAI 566
                         :|..|::.:  |::||:.....:|.:      ||:||           |:|:
  Fly   541 -------------RANLDIKCDSFRQMLMNLDRDNLQLR------TELAS-----------LKAV 575

  Fly   567 DNDIEMRTKLIEQLELTNSRYEQMRTHYEEKLSVLYCKIENTQKERDDVLANMTTSVSTPSKDSL 631
            ......|:..:|         :::|.| |..:               |||.|      |.||.
  Fly   576 YKQERDRSAALE---------KKVRIH-ESSI---------------DVLNN------TLSKQ-- 607

  Fly   632 KKVKTDYESKISHMQTEIRKLQN--AQREHIRSKQQLKSHEVRIGTLRNELNELKFAKVKLMKKM 694
                   |.:|..:..::.:.:|  .|:||.:.||                      |.|...|:
  Fly   608 -------ERQIEELTFKLNEKENMLTQKEHEKEKQ----------------------KKKFSSKL 643

  Fly   695 SQQSNRHKQEESRKSKEIAQLLKEQRRQKNAVLTLEAKVSAKEQI--LKRKTEEVIALRKSQRGK 757
            :.:|:::|:|...|.:|....|:|:.|.|:..|.|.:.:...|.:  |.|.......|.:..||.
  Fly   644 AVESDKNKREFELKLREQRVKLQERMRIKDEKLRLVSNILQSEDLPSLPRSQSSENILNEKDRGA 708

  Fly   758 SGQR-----APAHLTSKIAT-LDGFSTRSARHR--------WENLYRNILHAA------------ 796
            ...|     .||..|...|| ..|.:..:.|||        |      :.|.|
  Fly   709 YTARTEESSVPATRTDIYATPRHGAAAANNRHRRSRSAGDKW------LEHRAANPVPLGTIMQP 767

  Fly   797 --RNRQLITQLEKELERLILEREDLSRELNIMENGQT------ADRQTDEFNEVDNLKTNI---- 849
              :||:.:|:|           .|| :||.  .:|.|      .|..||...|....|.|:
  Fly   768 YLKNRKSVTKL-----------TDL-KELT--AHGTTKYCLVSQDADTDGDVETKLYKGNVIPTC 818

  Fly   850 ----SYIQENIEHVQQAIMEFEDTKDTVQSHVNK------IQSLLDEV--STVAEAKFILQKFSD 902
                ..:..::|.::|        |..|.|...|      |.:|....  |||..|:.:..:
  Fly   819 GGGAQVVFNDVECLKQ--------KSPVHSPTRKRPSNGNISALGGGAVPSTVTSAQDVASR--- 872

  Fly   903 TAIVMSCNLAIAESHLQEKESL 924
                  |||.| |.|..:|..:
  Fly   873 ------CNLGI-EGHSSKKSKI 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp31E	NP_001162935.1	KISc_KIF4	12..364	CDD:276823	129/437 (30%)
		KISc	13..370	CDD:214526	129/442 (29%)
		KASH_CCD	409..589	CDD:291334	32/181 (18%)
		RasGAP	<685..750	CDD:295371	17/66 (26%)
pav	NP_477025.1	KISc_KIF23_like	35..450	CDD:276819	128/428 (30%)
		Kinesin	42..452	CDD:278646	126/423 (30%)
		MKLP1_Arf_bdg	735..837	CDD:293148	25/129 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940