Protein Alignment Klp31E and Khc

DIOPT Version :9

• Sequence 1: NP_001162935.1
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Sequence 2: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 1036
• Identity: 269/1036 - (25%)
• Similarity: 465/1036 - (44%)
• Gaps: 247/1036 - (23%)

  Fly     8 INKDSSVRVAVRIRPQNSRELIDMCRI-----------CTTVTLGEPQIFLGSDKAFTFDYVFDT 61
            |..:.|::|..|.||.|..|.....:.           |.::          :.|.:.||.||..
  Fly     7 IPAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISI----------AGKVYLFDKVFKP 61

  Fly    62 NSNQCDIYSDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESSDSVQLGIIPRAVR 126
            |::|..:|::..:.:|...|.|||.|:.|||||.||||:||      |....|||:.|||||.|.
  Fly    62 NASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTM------EGVIGDSVKQGIIPRIVN 120

  Fly   127 HIFSGIEQLEGSSTSEHPAAGGSPQFSLAVQYIELYNEDIFDLLDPFNKNSNFKIHEDASGQITI 191
            .||:.|..:|.:.           :|.:.|.|.|:|.:.|.||||.  ...|..:|||.:....:
  Fly   121 DIFNHIYAMEVNL-----------EFHIKVSYYEIYMDKIRDLLDV--SKVNLSVHEDKNRVPYV 172

  Fly   192 SGASIKPIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLLTPSDNVPDNDLE 256
            .||:.:.:..|.|..:.:::|...|..|.|.||:.|||||::|.|.|:::.|         .:.:
  Fly   173 KGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENL---------ENQK 228

  Fly   257 TLTSKFHFVDLAGSERLKRTQATGERAREGISINCGLLALGNCISALGDKSKRALHVPYRDSKLT 321
            .|:.|.:.|||||||::.:|.|.|....|..:||..|.||||.||||.|.:|  .|:||||||||
  Fly   229 KLSGKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNK--THIPYRDSKLT 291

  Fly   322 RLLQDSLGGNSQTLMIACVSPSDRDFMETLNTLKYANRARNIKNKVKINQ-----------DQSS 375
            |:||:|||||::|.::.|.||:..:..||.:||.:..||:.:||.|.:|:           ::..
  Fly   292 RILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEK 356

  Fly   376 RTISQLRREIAALQLELLEYKQGKLI-----VDCE------------------------------ 405
            ...::|:.::..|::||..::.|:.:     ::.|
  Fly   357 EKNARLKGKVEKLEIELARWRAGETVKAEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQRTA 421

  Fly   406 -GNTTISDTFNENKLLLSEIKRLQQRLKSLQSTIATLTQRNADLKTNLDLNKWTSDDNSDVEIAK 469
             .|.:.|...||...|.:|.:||.|:|                             |:.|.||.:
  Fly   422 LANMSASVAVNEQARLATECERLYQQL-----------------------------DDKDEEINQ 457

  Fly   470 VVGQYMLEIEELQTKLIESEEHRKQMEIKATTSPRNAKPVYDSDIITKAKKDLERERELLMSRSL 534
             ..||   .|:|:.:::|.||                       :|..|:    ||.|.|.| .:
  Fly   458 -QSQY---AEQLKEQVMEQEE-----------------------LIANAR----REYETLQS-EM 490

  Fly   535 PGIQNQNVSSEE---------TEVA-SSDSEAEEV---VKDLEAIDNDIEMRTKLIEQLELTNSR 586
            ..||.:|.|::|         .|:| :.|.:::|:   .||::|::.:::.:..:.........:
  Fly   491 ARIQQENESAKEEVKEVLQALEELAVNYDQKSQEIDNKNKDIDALNEELQQKQSVFNAASTELQQ 555

  Fly   587 YEQMRTHYEEKLSVLYCKIENTQKERDDVLANMTTSV----STPSKDSLKKVKTDYESK---ISH 644
            .:.|.:|.:::::.:...:.....|....:|...:|:    |..:.....||:.|:...   ||.
  Fly   556 LKDMSSHQKKRITEMLTNLLRDLGEVGQAIAPGESSIDLKMSALAGTDASKVEEDFTMARLFISK 620

  Fly   645 MQTEIRKLQNAQREHIRSKQQLKSHEVRIGTLRNELNELKFAKVKLMKKMSQQSNRHK--QEESR 707
            |:||.:.:  |||......||..|:: :|.....:|.|.:..       :||...|.|  ||..|
  Fly   621 MKTEAKNI--AQRCSNMETQQADSNK-KISEYEKDLGEYRLL-------ISQHEARMKSLQESMR 675

  Fly   708 KSKEIAQLLKEQ---RRQKNAVLTLEAKVSAKEQILKRKTEEVIALRKSQRG---KSGQRAPAHL 766
            :::...:.|:||   .|::.|.|.....|||.....|::.||:.::..||..   ::..|..:.|
  Fly   676 EAENKKRTLEEQIDSLREECAKLKAAEHVSAVNAEEKQRAEELRSMFDSQMDELREAHTRQVSEL 740

  Fly   767 TSKIATLDGFSTRSARHRWE---NLYRNILHAARNRQLITQLEK----------ELERLIL---E 815
            ..:||        :.:|..:   ::::.:|.|  ::|:....||          ||:.:||   .
  Fly   741 RDEIA--------AKQHEMDEMKDVHQKLLLA--HQQMTADYEKVRQEDAEKSSELQNIILTNER 795

  Fly   816 REDLSRELNIMENGQTADRQTDEFNEVDNLKTNISYIQENIEHVQQAIMEFEDTKD----TVQSH 876
            ||...::|..:|     |....|...:.||:.  .::|:..:.:::.::..|..:|    ..:..
  Fly   796 REQARKDLKGLE-----DTVAKELQTLHNLRK--LFVQDLQQRIRKNVVNEESEEDGGSLAQKQK 853

  Fly   877 VNKIQSLLDEVSTVAEAKFILQKFSDTAIVMSCNLAIAESHLQ---EK----ESLLKEVKQ 930
            ::.:::.||:::.|.:     |...|.| .:.|.|...|..|:   |:    |:.|||.|:
  Fly   854 ISFLENNLDQLTKVHK-----QLVRDNA-DLRCELPKLEKRLRCTMERVKALETALKEAKE 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp31E	NP_001162935.1	KISc_KIF4	12..364	CDD:276823	133/362 (37%)
		KISc	13..370	CDD:214526	136/367 (37%)
		KASH_CCD	409..589	CDD:291334	39/192 (20%)
		RasGAP	<685..750	CDD:295371	19/69 (28%)
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	133/362 (37%)
		KISc	12..340	CDD:214526	136/367 (37%)
		Apolipoprotein	595..744	CDD:279749	41/158 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437937
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940