Protein Alignment Klp31E and CG14535

DIOPT Version :9

• Sequence 1: NP_001162935.1
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Sequence 2: NP_001285726.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Alignment Length: 1177
• Identity: 211/1177 - (17%)
• Similarity: 374/1177 - (31%)
• Gaps: 392/1177 - (33%)

  Fly    14 VRVAVRI--RPQNS----RELIDMCRICTTVTLGEPQI-------------FLGSDKAFTFDYVF 59
            |:|.:|:  |.:||    .:.:.:.:....|||.:|:.             .:.:.|.|.||.:|
  Fly    45 VKVMLRVADRDRNSGGTEPDFMALDKKKRQVTLTDPRTACPPPQAAQERAPMVAAPKMFAFDNLF 109

  Fly    60 DTNSNQCDIYSDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTM------GTGFDHESESSDSVQL 118
            .....|.|:.:..:.:::.:.|.|.:..:||.|...:|:..|:      |:|....|.|..:..|
  Fly   110 TGEDKQSDVCASALSEVIPAVLEGSDGCLLAMGYPATGQAQTVLGELGGGSGSGSASGSGVACSL 174

  Fly   119 GIIPRAVRHIFSGIEQLEGSSTSEHPAAGGSPQFSLAVQYI-------ELYNEDIFDLLDPFNKN 176
            |..|.|:..::.||::....|         ..:||:.|..:       :..::|:.        .
  Fly   175 GAAPCAIAWLYKGIQERRQKS---------GARFSVRVSAVGVSATKPDALSQDLL--------I 222

  Fly   177 SNFKIHEDASGQITISGASIKPIYQPHD---------------ALKYLQQGALARTTASTKMNDQ 226
            |:....:|:.|           ||...|               |..:|......|..:|......
  Fly   223 SHAAESDDSPG-----------IYLRDDFLGGPTELRAPTAERAALFLDSALAGRLKSSGSTASG 276

  Fly   227 SS------RSHALFTIFVRRQRLLTPSDNVPDNDLETLTSKFHFVDLAGSERLKRTQATGERARE 285
            ||      .|..:||:.| .|..|:....|...     .|:.|.:||.|...           |.
  Fly   277 SSGCAAPLESALIFTLHV-YQYSLSRKGGVAGG-----RSRLHIIDLGGCAN-----------RN 324

  Fly   286 GISINCGLLALGNCISAL--GDKSKRALHVPYRDSKLTRLLQDSLGG-NSQTLMIACVSPSDRDF 347
            |   ...|..:||.:.|:  |.:     |.|::|..||.||:|.|.. .....::|.|.| ::.:
  Fly   325 G---GLPLSGIGNILLAILSGQR-----HPPHKDHPLTPLLKDCLAPITCHVAIVAHVRP-EQSY 380

  Fly   348 METLNTLKYANRARNIKNKVKINQDQSSRTISQLRREIAALQLEL-LEYKQGKLIVDCEGNTTIS 411
            .:.|:|::.|:|                  |.:|||....:.:.| :...||     ..||.:
  Fly   381 QDALSTIQIASR------------------IHRLRRRKHRVPMPLAVGLAQG-----LGGNGS-- 420

  Fly   412 DTFNENKLLLSEIKRLQQRLKSLQSTIATLTQRNADLKTNLDLNKWTSDDNSDVEIAKVVGQYML 476
                                    |..:.....::::..:..:....:||.:|.|...|   |:.
  Fly   421 ------------------------SAGSGADPSSSEISADTVIYMGPNDDATDGEHPPV---YLP 458

  Fly   477 EI-----EELQTKLIESEEHRKQMEIKATTSPRNAKPVYDSDIITKAKKDLERERELLMSRSLPG 536
            .:     ..:.:|.::.....|.....|:.||...|....::   ||||             |||
  Fly   459 SLTAGDNRGVMSKALKGSGLEKPPSKSASNSPMMMKKAMAAE---KAKK-------------LPG 507

  Fly   537 IQNQNVSSEETEVASSDSEAEEVVKDLEAIDNDIEMRTKLIEQLELTNSRYEQMRTHYEEKLSVL 601
            ....::..:....|.|..........::|:.:.|.:...::.:
  Fly   508 SHTGSLKRQAGAGACSSPMIPHEQPQIQAMGSPIPIPRHMVSK---------------------- 550

  Fly   602 YCKIENTQKERDDVLANMTTSVSTPSKDSLKKVKTDYESKISHMQTEIRKLQNAQREHIRSKQQL 666
                              .:.|.:|....:::....  :.:..::..:||:...|........:.
  Fly   551 ------------------GSMVPSPKGSPMRRAHPG--AALEQLEAGMRKITEEQWIDGPRVSRA 595

  Fly   667 KSHEVRIGTLRNELNELKFAKVKLMKKMSQ----------------QSNRHKQEESRKSKEIAQL 715
            |..|.|  .|..|:|.:|..:..:....||                |:..:...::.|...|.|.
  Fly   596 KVAEAR--HLMREVNHVKQCETWVDGPKSQSCRSLTACNLPAAGGSQTQGYGFMDAHKKTMIRQW 658

  Fly   716 LKEQRRQ--------KNAVLTLEAKVSAKEQILKRKT-----------EEVIALRK--------- 752
            ::.|..|        .|:...|..|:|.    ||:|:           |..:.|.:
  Fly   659 VENQTTQVFQSTVSASNSPTALHWKLSQ----LKQKSLDLPDRPAFNPEPSLDLNQPCFESLPLL 719

  Fly   753 -------SQRGKSGQRAPAHLTSKIATLDG-FSTRSARHRWENLYRNILHAARNRQLITQLEKEL 809
                   .:...||   |:.:...:..||. ..:|....  :||:|.:.......||     .|.
  Fly   720 DPAPPDGDEDEDSG---PSEVPPALPLLDDPLGSRDISQ--DNLHRMLSRHVSREQL-----HEA 774

  Fly   810 ERLILEREDLSRELNIMENGQTADRQTDEFNEVDNLKTNISYIQENIEHVQQAIMEFEDTKDTVQ 874
            | |:..|...|.        ..:.|..|         ..:...:|.|.....     .|......
  Fly   775 E-LVASRASSSH--------HPSQRSID---------CGLQVTEEEIARTMS-----RDRDHDPS 816

  Fly   875 SHVNKIQSLLDEVSTVAEAKFILQKFSDTAIVMSCNLAIAESHLQEKESLLKEVKQESGIQQQIL 939
            :|.....|..|.:|.|:......:.||:      |.               :..:|:.....::.
  Fly   817 AHPLSALSHCDNISFVSSFNMACESFSE------CG---------------ERARQQFDQLARLH 860

  Fly   940 QHFLSQNSNVHIADIFDSLNLKGSNIAS-------SVNPGSQKSLISNATYDI-PQDDKNSEFHQ 996
            :.|.||   :.:|::..|..|..::|.|       ..|.| |.|:.|...|.: |...|.
  Fly   861 EIFTSQ---LAMAEVTPSAALFRTDIGSVFSEPVYHFNVG-QSSVCSEPAYRLTPSPPKQ----- 916

  Fly   997 VEMRRTTSRSPS------------------------PLGNSDP-FDKSPKVRRRTAKRQDLLFGD 1036
                  .|.|||                        |.|.||| ..|..|  |.|.:..|:
  Fly   917 ------PSHSPSQGSLPSLNGIMEIAGMDDYALLRQPDGASDPNLQKGEK--RFTPQHDDI---- 969

  Fly  1037 TELSEQT 1043
            .||.|::
  Fly   970 CELDEKS 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp31E	NP_001162935.1	KISc_KIF4	12..364	CDD:276823	86/405 (21%)
		KISc	13..370	CDD:214526	86/411 (21%)
		KASH_CCD	409..589	CDD:291334	24/184 (13%)
		RasGAP	<685..750	CDD:295371	16/99 (16%)
CG14535	NP_001285726.1	Motor_domain	44..394	CDD:277568	86/420 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100