Protein Alignment Klp31E and Klp64D

DIOPT Version :10

• Sequence 1: NP_609398.2
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Sequence 2: XP_312517.6
• Gene: Klp64D / 1273532
• VectorBaseID: AGAMI1_004514
• Length: 685
• Species: Anopheles gambiae
• Alignment Length: 729
• Identity: 220/729 - (30%)
• Similarity: 343/729 - (47%)
• Gaps: 153/729 - (20%)

  Fly    13 SVRVAVRIRPQNSREL-------IDMCRICTTVTLGEPQIFLGS-DKAFTFDYVFDTNSNQCDIY 69
            :|||.||:||.:..||       |.:.:...::|:.:|...... .|.:.||.||..:|.|.|:|
Mosquito    14 NVRVVVRVRPMDKSELDVGSQNVIKVDKSNRSITVVKPNANSSEPPKVYYFDNVFGEDSTQIDLY 78

  Fly    70 SDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESSDSVQL-GIIPRAVRHIFSGIE 133
            .|....:||..|.|||.|:|||||||:||||||       |.|:||.|. ||||....|||.
Mosquito    79 VDTARPIVDKVLEGYNGTILAYGQTGTGKTYTM-------SGSADSPQTKGIIPNTFAHIFG--- 133

  Fly   134 QLEGSSTSEHPAAGGSPQ-FSLAVQYIELYNEDIFDLLDPFNKNSNFKIHEDASGQITISGASIK 197
                     |.|.|...| |.:.|.|:|:|||::.|||.. ..|.:.::.|.|...:.:...|..
Mosquito   134 ---------HIARGKENQKFLVRVSYMEIYNEEVRDLLGK-ELNKSLEVKERADIGVFVKDLSGY 188

  Fly   198 PIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLLTPSDNVPDNDLETLTSKF 262
            .::...|....::.|...|...:||||.:||||||:|:|.|.      .|:............|.
Mosquito   189 VVHNADDLDNIMKLGNKNRVVGATKMNSESSRSHAIFSITVE------SSETDEAGRQYVRMGKL 247

  Fly   263 HFVDLAGSERLKRTQATGERAREGISINCGLLALGNCISALGDKSKRALHVPYRDSKLTRLLQDS 327
            ..||||||||..:||::|.|.:|...||..|..|||.||||.|  .::.|:|||:||||||||||
Mosquito   248 QLVDLAGSERQSKTQSSGLRLKEATKINLSLSVLGNVISALVD--GKSTHIPYRNSKLTRLLQDS 310

  Fly   328 LGGNSQTLMIACVSPSDRDFMETLNTLKYANRARNIKNKVKINQDQSSRTISQLRREIAALQLEL 392
            |||||:|:|.|.:||:|.:::||::||:||.||::|:|...||::.....:...:.||..|:.:|
Mosquito   311 LGGNSKTVMCASISPADSNYVETISTLRYACRAKSIQNLAHINEEPKDALLRHFQEEIEELKRQL 375

  Fly   393 LE--YKQG---------------------KLIVDCEGNTTISDTFNENKLLLSEIKRLQQRLKSL 434
            .|  ::||                     .:..:|:     .|...|.:.|  |.|..|::.|:.
Mosquito   376 EEGIFQQGIESGDEEEEEDGDGEGEDEEDAVEEECD-----PDADRERERL--ERKEKQRKEKAR 433

  Fly   435 QSTIATLTQRNADLKTNLDLNKWTSDDNSDVEIAKVVGQYMLEIEELQTKLIESEEHRKQMEIKA 499
            :      .:..:|.:..| |.|...::..:::.||      .|.::|:.||
Mosquito   434 E------RKEKSDAEKEL-LEKKAMENQQELKKAK------SEQDQLRAKL-------------- 471

  Fly   500 TTSPRNAKPVYDSDIITKAKKDLERERELLMSRSLPGIQNQNVSSEETEVASSDSEAEEVVKDLE 564
             :|..|...|...:::.|||     |:|||:..|:..::.:..:..|.:......|||.:  |:|
Mosquito   472 -SSLENKILVGGENLLEKAK-----EQELLLENSITELEQRTKTERELKENLQKIEAERI--DIE 528

  Fly   565 ----AIDNDIEMRTKLIEQL---------ELTNSRYEQMRTHYEEKLSVLYCKIENTQK-ERDDV 615
                ::..:...:||.::::         ||.:.:.||.|    ||..:    .||.:. .|:..
Mosquito   529 ERYSSLQEECVGKTKKLQRVMSMLMSIKSELADQQQEQQR----EKEGI----YENIRSLSRELA 585

  Fly   616 LANMTTSVSTPSKDSLKKVKTDYES---KISHMQTEIRKLQ--------NAQREHIRSKQQLKSH 669
            |..:..:...|.         :|:|   |.:|...:|.:.|        |..|::|        .
Mosquito   586 LCELVINSYIPK---------EYQSMIEKFTHWNEDIGEWQLKCVAYTGNNMRKNI--------P 633

  Fly   670 EVRIGTLRNELNEL 683
            |.::.|...:|.:|
Mosquito   634 EPKVNTKETDLIDL 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp31E	NP_609398.2	KISc_KIF4	12..364	CDD:276823	147/360 (41%)
		Mplasa_alph_rch	<372..>748	CDD:275316	69/360 (19%)
		SMC_prok_B	622..>899	CDD:274008	14/73 (19%)
		Rcc_KIF21	798..870	CDD:410202
Klp64D	XP_312517.6	None