DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5355 and AT1G76140

DIOPT Version :9

Sequence 1:	NP_609397.2	Gene:	CG5355 / 34421	FlyBaseID:	FBgn0032242	Length:	756	Species:	Drosophila melanogaster
Sequence 2:	NP_177741.3	Gene:	AT1G76140 / 843946	AraportID:	AT1G76140	Length:	795	Species:	Arabidopsis thaliana

Alignment Length:	777	Identity:	360/777 - (46%)
Similarity:	485/777 - (62%)	Gaps:	40/777 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PLLYRR-----ICQIVVPKTLPRNYIHRELPSNLTR----------AMPSTLSAKLAYPVARKDE 57
            |.:.||     :.|..:..:|..|......|::::|          ...|....:|.||..|:|:
plant    20 PTITRRLRINILRQSPLSSSLLLNETFSNRPNSVSRRCYCSSSAIMGSSSVFGEQLQYPATRRDD 84

  Fly    58 SVAEDFHGTQIKDVYRWLEDPDSTETEEFVNAQNSISRPFLENGEEWKKLNTKLTKLWNYPKYGC 122
            ||.:|:||.:|.|.||||||||:.|.:|||.:|..::...||..|..:||...:|||.::|:|..
plant    85 SVVDDYHGVKIGDPYRWLEDPDAEEVKEFVQSQVKLTDSVLEKCETKEKLRQNITKLIDHPRYDS 149

  Fly   123 PMRYGNYYYYFMNTGLQNQSVMYQQKSLGDESESKVFLDPNTLSEDGTIALTQKAFSEDGKYMAY 187
            |.|.|:.|:||.|||||.|||:|.|.:|  ::|.:|.|||||||:|||:||...:.|||.||:||
plant   150 PFRQGDKYFYFHNTGLQAQSVLYMQDNL--DAEPEVLLDPNTLSDDGTVALNTFSVSEDAKYLAY 212

  Fly   188 GLSESGSDWIKILIRDAETGKDLSEVLEKVKFSEISWTKDNKGFFYGRYPDQDGKTD---GSETK 249
            |||.|||||:.|.:...|..|...:.|..|||:.|:||.|:|||||||||......|   |:||.
plant   213 GLSSSGSDWVTIKLMKIEDKKVEPDTLSWVKFTGITWTHDSKGFFYGRYPAPKEGEDIDAGTETN 277

  Fly   250 QNENQKLYYHRVGESQDKDTLVVEFPEEPSWRIQSTVSDCGKYLILAIVKDCRD-NIVFYADLTP 313
            .|...:||||.:|..|.:|.|.....|.|.:...:.|:|.|||||::|.:.|.. |.::|.|:|.
plant   278 SNLYHELYYHFIGTDQSQDILCWRDNENPKYMFGAEVTDDGKYLIMSIGESCDPVNKLYYCDMTS 342

  Fly   314 ---GAE----ITSKLNVKKIVEKFEADYDYITNEGSKIFFRTNKNAPNYQVIAIDFNNSAEDKWE 371
               |.|    .:|.|...|:|:.|:|.|..|:|:.:...|.|||:||.|:::.:|...  .:.|.
plant   343 LSGGLESFRGSSSFLPFIKLVDTFDAQYSVISNDETLFTFLTNKDAPKYKLVRVDLKE--PNSWT 405

  Fly   372 TLIAEHKSDVLDWVKCVDNDKLLVCYIRDVKSVLQVNSLKDGTLLREFDLDIGTIVGTSGEKKYS 436
            .::.||:.|||.....|:.:.|:.||:.|||.:||:..||.|:||.:..||||::...|..:|.:
plant   406 DVVEEHEKDVLASACAVNGNHLVACYMSDVKHILQIRDLKSGSLLHQLPLDIGSVSDVSARRKDN 470

  Fly   437 EIFYNFSSFLNPGSIYRYDFKTPDKSPSVFREIKLNLEGFRREDYAVEQIFYKSKDGTKVPMFII 501
            ..|::|:|||.||.||:.|.........||||:  .:.||.||.:...|:||.||||||:||||:
plant   471 TFFFSFTSFLTPGVIYKCDLANESPEVKVFREV--TVPGFDREAFQAIQVFYPSKDGTKIPMFIV 533

  Fly   502 RKKRDSVE-PRPCLLYGYGGFNISMLPSFGLSGLMFIDTFDGVLAYPNLRGGGEYGEKWHNGGRL 565
            .||...:: ..|||||.|||||||:.|||..|.::.......|..:.|:||||||||:||..|.|
plant   534 AKKDIKLDGSHPCLLYAYGGFNISITPSFSASRIVLSKHLGVVFCFANIRGGGEYGEEWHKAGSL 598

  Fly   566 LNKQNVFDDFQAAAEYLIENKYTTKDRLAIQGGSNGGLLVGSCINQRPDLFGAAVAQVGVMDMLR 630
            ..|||.||||.:.||||:...||...:|.|:||||||||||:||||||||:|.|:|.||||||||
plant   599 AKKQNCFDDFISGAEYLVSAGYTQPSKLCIEGGSNGGLLVGACINQRPDLYGCALAHVGVMDMLR 663

  Fly   631 FHKFTIGHAWCSDYGNPSEKEHFDNLYKFSPLHNVHTPKGAET----EYPSTLILTADHDDRVSP 691
            ||||||||||.||||....:|.|..|.|:||||||..|...:|    :||||::|||||||||.|
plant   664 FHKFTIGHAWTSDYGCSENEEEFHWLIKYSPLHNVKRPWEQQTDHLVQYPSTMLLTADHDDRVVP 728

  Fly   692 LHSLKFIAALQEAV---RDSEFQKNPVLLRVYQKAGHGAGKPTSKRIEEATDILTFLSKSLN 750
            |||||.:|.||..:   .|:..|.||::.|:..|||||||:||.|.|:||.|..:|::|.:|
plant   729 LHSLKLLATLQHVLCTSLDNSPQMNPIIGRIEVKAGHGAGRPTQKMIDEAADRYSFMAKMVN 790

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5355	NP_609397.2	Peptidase_S9_N	51..467	CDD:280970	183/426 (43%)
		Aes	442..750	CDD:223730	175/315 (56%)
		Peptidase_S9	541..752	CDD:278741	128/217 (59%)
AT1G76140	NP_177741.3	Peptidase_S9_N	78..501	CDD:280970	183/426 (43%)
AT1G76140	NP_177741.3	Peptidase_S9	560..792	CDD:278741	132/231 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	345	1.000	Domainoid score	I231
eggNOG	1	0.900	-	-		E1_COG1505
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2042
Inparanoid	1	1.050	678	1.000	Inparanoid score	I146
OMA	1	1.010	-	-		QHG63012
OrthoDB	1	1.010	-	-		D225446at2759
OrthoFinder	1	1.000	-	-		FOG0005219
OrthoInspector	1	1.000	-	-		mtm1131
orthoMCL	1	0.900	-	-		OOG6_101804
Panther	1	1.100	-	-	O	PTHR42881
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3731
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840