Protein Alignment CG5355 and Prepl

DIOPT Version :10

• Sequence 1: NP_609397.2
• Gene: CG5355 / 34421
• FlyBaseID: FBgn0032242
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: XP_063117671.1
• Gene: Prepl / 298771
• RGDID: 1310143
• Length: 761
• Species: Rattus norvegicus
• Alignment Length: 805
• Identity: 181/805 - (22%)
• Similarity: 316/805 - (39%)
• Gaps: 187/805 - (23%)

  Fly     4 IFRGPLLY-----------RRICQIVVP---KTLPRNY------IHRELPSNLTRAMPS-TLSAK 47
            :|.|.|.|           :..|.:..|   :...:||      .::...|.|.|.:|| :.|.|
  Rat    29 LFLGALKYSIPHLGKCMPKQNYCNVADPYYNRLRLKNYRLTKCLQNKPKISELARNIPSRSFSRK 93

  Fly    48 LAYPVARKDESVAEDFHGTQIKDVYRWLEDPDSTETEEFVNAQNSISRPFLENGEEWKKLNTKL- 111
            ...||  |.||                               :||||    |:.:.::|:.|:|
  Rat    94 DLLPV--KPES-------------------------------ENSIS----EDMDAFEKVRTRLE 121

  Fly   112 -TKLWNYPKYGCPMRYGNYYYYFMNTGLQNQSVMYQQKSLGDESESKVFLDPNTLSEDGTIALTQ 175
             .....|......:::|.:.||      |....:.:.|.  :|::|..:.....|.|   :.|.|
  Rat   122 TQPQEEYEIVNAEIKHGGFVYY------QEGCCLVRSKD--EEADSDNYEVLFNLEE---LKLEQ 175

  Fly   176 K-----AFSEDGKYMAYGLSESGSDWIKILIRDAETG-----KDLSEVLEKVKFSEIS---WTKD 227
            .     ..:.|.||:|          .||...|:||.     |...:...:..|..:|   |.||
  Rat   176 PFIDCIRVAPDEKYVA----------AKIRAEDSETSTCIVVKLSDQPAMEASFPNVSSFEWVKD 230

  Fly   228 NKG---FFYG-----RYPDQDGKTDGSETKQNENQKLYYHRVGESQDKDTLVVEFPEEPSWRIQS 284
            .:.   .||.     |..|....|.| :.|:||.   :|      .:||         ||:.:..
  Rat   231 EEDEDVLFYTFQRNLRCHDVYRATFG-DNKRNER---FY------TEKD---------PSYFVFL 276

  Fly   285 TVSDCGKYLILAIVKDCRDNIVFYADLTPGAEITSKLNVKKIVEK-FEADYDYITNEGSKIFFRT 348
            .::...::|.|.|:......:.....|:|       .:...:::| ......|:.:...:::..|
  Rat   277 YLTKDSRFLTLNIMNKTTSEVWLIDGLSP-------WDPPMLIQKRIHGMLYYVEHRDDELYILT 334

  Fly   349 NKNAP-NYQVIAIDFNNSAEDKWETLIAEHKSDVLDWVKCVDNDKL---LVCYIRDVKSVLQVN- 408
            |...| .::::....:..|...|:......::     .|.||.|..   .|.:::. .::|.||
  Rat   335 NVGEPTEFKLMRTAADAPAIMNWDLFFTMKRN-----TKVVDLDMFKDHCVLFLKH-SNLLYVNV 393

  Fly   409 -SLKDGTLLREFDLD---IGTIVGTSGEKKYSEIFYNFSSFLNPGSIYRYDF-------KTPDKS 462
             .|.|.: :|...|.   .|.|:.|:.:.|...  :...|.:.|...|.|.|       :|..:.
  Rat   394 IGLADDS-VRSLKLPPWACGFIMDTNSDPKNCP--FQLCSPIRPPKYYTYKFAEGKLFEETGHED 455

  Fly   463 PSVFREIKLNLEGFRREDYAVEQIFYKSKDGTKVPMFIIRK-KRDSVEPRPCLLYGYGGFNISML 526
            |.......|.:|.             |||||..|||.:..| ..:.::.:|.|::.||.:.:.:.
  Rat   456 PITKTSRVLRIEA-------------KSKDGKLVPMTVFHKTDSEDLQRKPLLVHVYGAYGMDLK 507

  Fly   527 PSFGLSGLMFIDTFDG-VLAYPNLRGGGEYGEKWHNGGRLLNKQNVFDDFQAAAEYLIENKYTTK 590
            .:|.....:.:|  || :|||.::|||||.|.:||..|||..|.|...|.:|..:.|....::..
  Rat   508 MNFRPERRVLVD--DGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLEACIKTLHSQGFSQP 570

  Fly   591 DRLAIQGGSNGGLLVGSCINQRPDLFGAAVAQVGVMDMLRFHKFT---IGHAWCSDYGNP-SEKE 651
            ....:...|.||:|||:..|.:|:|..|...:...:|:|.....|   :......::||| |:::
  Rat   571 SLTTLSAFSAGGVLVGALCNSKPELLRAVTLEAPFLDVLNTMMDTTLPLTLEELEEWGNPSSDEK 635

  Fly   652 HFDNLYKFSPLHNVHTPKGAETEYPSTLILTADHDDRVSPLHSL-KFIAALQEAVRD-----SEF 710
            |.:.:.::.|..|: .|:    .|||..|...::|:|| ||..: .:...|:|||.:     .|.
  Rat   636 HKNYIKRYCPCQNM-KPQ----HYPSVHITAYENDERV-PLKGIVNYTEKLKEAVAEHSKGAGEG 694

  Fly   711 QKNPVLLRVYQKAGHGAGKPTSKRI 735
            .:.|.::...|..|:...:.:.|::
  Rat   695 YQPPNIVLDIQPGGNHVIEDSHKKV 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5355	NP_609397.2	PreP	45..749	CDD:441114	168/743 (23%)
Prepl	XP_063117671.1	None