DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ip259 and SPCP1E11.08

DIOPT Version :9

Sequence 1:	NP_001260347.1	Gene:	Ip259 / 34419	FlyBaseID:	FBgn0025366	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_588561.1	Gene:	SPCP1E11.08 / 2539413	PomBaseID:	SPCP1E11.08	Length:	260	Species:	Schizosaccharomyces pombe

Alignment Length:	259	Identity:	163/259 - (62%)
Similarity:	205/259 - (79%)	Gaps:	1/259 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPQNEYMERHRKLYGRRLDYEERKRKKEARLPKDRARKARKLRGIKAKLFNKERRNEKIQIKKKI 65
            ||||||:|...:.:|||.|:|||||||.||...|.:..|:|.|||||||:.::||.||||:||.|
pombe     1 MPQNEYIEESIRKHGRRFDHEERKRKKAAREAHDASLYAQKTRGIKAKLYQEKRRKEKIQMKKTI 65

  Fly    66 QAHEEKKVKKQEEKVE-DGALPHYLLDRGIQSSAKVLSNMIKQKRKEKAGKWDVPIPKVRAQSDA 129
            :.|||:...::....: .||:|.|||||..:|.||:||:.:||||||||.|:.||:|:||..::.
pombe    66 KQHEERNATQRGSDAQTQGAVPTYLLDREQESQAKMLSSAVKQKRKEKAAKYSVPLPQVRGVAEE 130

  Fly   130 EVFKVLKTGKTKRKAWKRMVTKVTFVGENFTRKPPKFERFIRPMGLRMKKAHVTHPELKATFNLP 194
            |:|||::|||:|:.:||||:||.||||:.|||:|.|:|||||||.||.|||:|||.||..|..||
pombe   131 EMFKVIRTGKSKKNSWKRMITKATFVGDGFTRRPVKYERFIRPMALRQKKANVTHKELGVTMQLP 195

  Fly   195 IIGVKKNPSSPMFTSLGVITKGTVIEVNISELGLVTQTGKVVWGKYAQVTNNPENDGVINAVLL 258
            ||||||||.||.:|.|||:|||||||||:|||||||..||||||||||:|||||.||.:||:||
pombe   196 IIGVKKNPQSPTYTQLGVLTKGTVIEVNVSELGLVTSGGKVVWGKYAQITNNPELDGCVNALLL 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ip259	NP_001260347.1	NSA2	4..259	CDD:211393	160/256 (63%)
SPCP1E11.08	NP_588561.1	NSA2	4..259	CDD:211393	158/254 (62%)
SPCP1E11.08	NP_588561.1	Ribosomal_S8e	31..259	CDD:279534	141/227 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	295	1.000	Domainoid score	I266
eggNOG	1	0.900	-	-		E1_COG2007
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5844
Inparanoid	1	1.050	333	1.000	Inparanoid score	I509
OMA	1	1.010	-	-		QHG53649
OrthoFinder	1	1.000	-	-		FOG0004993
OrthoInspector	1	1.000	-	-		oto101955
orthoMCL	1	0.900	-	-		OOG6_102245
Panther	1	1.100	-	-	LDO	PTHR12642
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R842
SonicParanoid	1	1.000	-	-		X3527
TreeFam	1	0.960	-	-
	14	13.860