Protein Alignment Ip259 and NSA2

DIOPT Version :9

• Sequence 1: NP_001260347.1
• Gene: Ip259 / 34419
• FlyBaseID: FBgn0025366
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_055701.1
• Gene: NSA2 / 10412
• HGNCID: 30728
• Length: 260
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 195/260 - (75%)
• Similarity: 227/260 - (87%)
• Gaps: 1/260 - (0%)

  Fly     1 MPQNEYMERHRKLYGRRLDYEERKRKKEARLPKDRARKARKLRGIKAKLFNKERRNEKIQIKKKI 65
            ||||||:|.|||.||.||||.|:|||||:|...:|::||:|:.|:||||::|:|..||||:||.|
Human     1 MPQNEYIELHRKRYGYRLDYHEKKRKKESREAHERSKKAKKMIGLKAKLYHKQRHAEKIQMKKTI 65

  Fly    66 QAHEEKKVK-KQEEKVEDGALPHYLLDRGIQSSAKVLSNMIKQKRKEKAGKWDVPIPKVRAQSDA 129
            :.||::..| |.:||...||:|.|||||..||.|||||||||||||||||||:||:||||||.:.
Human    66 KMHEKRNTKQKNDEKTPQGAVPAYLLDREGQSRAKVLSNMIKQKRKEKAGKWEVPLPKVRAQGET 130

  Fly   130 EVFKVLKTGKTKRKAWKRMVTKVTFVGENFTRKPPKFERFIRPMGLRMKKAHVTHPELKATFNLP 194
            ||.||::|||.|:||||||||||.|||:.|||||||:||||||||||.||||||||||||||.||
Human   131 EVLKVIRTGKRKKKAWKRMVTKVCFVGDGFTRKPPKYERFIRPMGLRFKKAHVTHPELKATFCLP 195

  Fly   195 IIGVKKNPSSPMFTSLGVITKGTVIEVNISELGLVTQTGKVVWGKYAQVTNNPENDGVINAVLLV 259
            |:|||||||||::|:|||||||||||||:||||||||.|||:|||||||||||||||.|||||||
Human   196 ILGVKKNPSSPLYTTLGVITKGTVIEVNVSELGLVTQGGKVIWGKYAQVTNNPENDGCINAVLLV 260

  Fly   260  259
            Human   261  260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ip259	NP_001260347.1	NSA2	4..259	CDD:211393	190/255 (75%)
NSA2	NP_055701.1	NSA2	4..260	CDD:211393	190/255 (75%)
		Nuclear localization signal. /evidence=ECO:0000255|PROSITE-ProRule:PRU00768	11..18		4/6 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..41		11/20 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147081
Domainoid	1	1.000	350	1.000	Domainoid score	I1022
eggNOG	1	0.900	-	-		E1_COG2007
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5844
Inparanoid	1	1.050	399	1.000	Inparanoid score	I1949
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53649
OrthoDB	1	1.010	-	-		D1079827at2759
OrthoFinder	1	1.000	-	-		FOG0004993
OrthoInspector	1	1.000	-	-		oto91359
orthoMCL	1	0.900	-	-		OOG6_102245
Panther	1	1.100	-	-	LDO	PTHR12642
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R842
SonicParanoid	1	1.000	-	-		X3527
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800