Protein Alignment Cnot4 and MOT2

DIOPT Version :10

• Sequence 1: NP_001260343.1
• Gene: Cnot4 / 34416
• FlyBaseID: FBgn0051716
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_010991.3
• Gene: MOT2 / 856799
• SGDID: S000000870
• Length: 587
• Species: Saccharomyces cerevisiae
• Alignment Length: 672
• Identity: 180/672 - (26%)
• Similarity: 286/672 - (42%)
• Gaps: 164/672 - (24%)

  Fly     2 NGLS-------SNDDAVECPLCMEPLEVDDLTFFPCTCGYQICRFCWHRIRTDE--NKLCPACRK 57
            |.||       |.|:...||||:||:::.|..||||.||||||:||::.||.:.  |..|||||:
Yeast    15 NALSNFDTSFLSEDEEDYCPLCIEPMDITDKNFFPCPCGYQICQFCYNNIRQNPELNGRCPACRR 79

  Fly    58 EYPENPADFKPLSQEEM------IAFKSQKRQ-RDQQRKQKITENRKHLANVRVVQKNLVFVVGL 115
            :|.:....:..||.||:      :|.|.::|: |:::||:....|||||:..||:|||||:|||:
Yeast    80 KYDDENVRYVTLSPEELKMERAKLARKEKERKHREKERKENEYTNRKHLSGTRVIQKNLVYVVGI 144

  Fly   116 PPRLADADI---LKKHEYFGKYGKIHKVVINPSTTYAGVQV-----RVGPSASAYVTYVNNSDAL 172
            .|.:...::   ||..:|||:||||:|:|:|..|.::....     ...|....|:|:.:..||.
Yeast   145 NPPVPYEEVAPTLKSEKYFGQYGKINKIVVNRKTPHSNNTTSEHYHHHSPGYGVYITFGSKDDAA 209

  Fly   173 RAIQSVNNIMIDGRLIKTSLGTTKYCSHFMKNQQCPKGDCMYLHELGDPEASFTKEEMHQGKHLE 237
            |.|..|:...:||||||.:.|||||||.:::...||..:||:|||.|:...||.|.|:|..:..:
Yeast   210 RCIAQVDGTYMDGRLIKAAYGTTKYCSSYLRGLPCPNPNCMFLHEPGEEADSFNKRELHNKQQAQ 274

  Fly   238 YE--------KRLHDTLIASLGPNATGIVNGNGASKANVAIPSSSSASSSSSGSGTNGSSASGNA 294
            .:        ..:|:.:..|...:.|.:::.|.....:.|...:.....|.:.:||
Yeast   275 QQSGGTAFTRSGIHNNISTSTAGSNTNLLSENFTGTPSPAAMRAQLHHDSHTNAGT--------- 330

  Fly   295 QQKEAWPSLSVSPIN------GKEAAATATSSSGKSKREKLRNEKRHEKNKAKNKNGSNTN---A 350
                  |.|:.:|:.      |...:||..:|...|                  ||.|:.|   .
Yeast   331 ------PVLTPAPVPAGSNPWGVTQSATPVTSINLS------------------KNSSSINLPTL 371

  Fly   351 NASNKENYVPETR---SSTSTETFAEATADAPASTKAEPPQASSNRTRADRGKDRTTASAKEQKK 412
            |.|...:..|.|.   :||:|.|...||:.:..|                  |.:.:.:|:|.|.
Yeast   372 NDSLGHHTTPTTENTITSTTTTTNTNATSHSHGS------------------KKKQSLAAEEYKD 418

  Fly   413 SKEAAPAPAASKPAERVET---SESTIRQKKAEVTESCEDNLPQKRLAGTNVQRSVSSCSENSEG 474
                 |..|.....:.::.   |.|..:::...:..:..|....|:..           |..|..
Yeast   419 -----PYDALGNAVDFLDARLHSLSNYQKRPISIKSNIIDEETYKKYP-----------SLFSWD 467

  Fly   475 HVSESSLSEKSLTGDYVE-------EKCNSVNSESQQESVKFQEELEKSNEAIVEAETILPTAES 532
            .:..|..|:.:|....||       :...||        |:|   |:..|..:.:..||  |..:
Yeast   468 KIEASKKSDNTLANKLVEILAIKPIDYTASV--------VQF---LQSVNVGVNDNITI--TDNT 519

  Fly   533 SEDISPAAVAPGNGEVEGCLPVVDPVEPPSLADNGSRVTDALSKLNIFDDTPSFFTSPSFQQAPI 597
            .....|..:.          .|...::||               ||:....|..| .|. .:.||
Yeast   520 KTPTQPIRLQ----------TVSQQIQPP---------------LNVSTPPPGIF-GPQ-HKVPI 557

  Fly   598 LKNKL-DLEMRQSHLPDLVNDI 618
            .:.:: |...|.|  .||:|.:
Yeast   558 QQQQMGDTSSRNS--SDLLNQL 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cnot4	NP_001260343.1	MOT2	5..>235	CDD:227502	104/253 (41%)
		cwf18	312..>386	CDD:462423	19/79 (24%)
MOT2	NP_010991.3	MOT2	9..560	CDD:227502	174/651 (27%)