Protein Alignment Mdh1 and MDH1

DIOPT Version :9

• Sequence 1: NP_001285803.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_012838.1
• Gene: MDH1 / 853777
• SGDID: S000001568
• Length: 334
• Species: Saccharomyces cerevisiae
• Alignment Length: 364
• Identity: 90/364 - (24%)
• Similarity: 133/364 - (36%)
• Gaps: 83/364 - (22%)

  Fly     1 MAEPIRVVVTGAAGQIAYSLLYMIARGEVFGKDQPIVLHLLDIPPMVGVLEGVVMELADCALPLL 65
            :|.|.:|.|.||.|.|...|..::....     :...|.|.|:..    .:||..:|:.
Yeast    14 VANPYKVTVLGAGGGIGQPLSLLLKLNH-----KVTDLRLYDLKG----AKGVATDLSH------ 63

  Fly    66 VEVVPTTDPAVGF------------KDVSAAFLVGAMPRKEGMERKDLLSANVKIFRTQGQALDK 118
               :||.....||            ||.....:...:|||.||.|.||.:.|..|.|....|..:
Yeast    64 ---IPTNSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPGMTRDDLFAINASIVRDLAAATAE 125

  Fly   119 FAKKDVKVLVVGNPANTN----ALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGVPISAVK 179
            .| .:..:||:.||.|:.    |.|..:.....|::.| .:|.||..|     ||:.   ||.|:
Yeast   126 SA-PNAAILVISNPVNSTVPIVAQVLKNKGVYNPKKLF-GVTTLDSIR-----AARF---ISEVE 180

  Fly   180 N-------IIIWGNHSS-TQYPDAGQA--KVTANGTVKSVVDAINDNGYLQGSFVETVQKRGAAV 234
            |       :.:.|.||. |..|...|.  |:.::.....::..|...|      .|.|:.:..|
Yeast   181 NTDPTQERVNVIGGHSGITIIPLISQTNHKLMSDDKRHELIHRIQFGG------DEVVKAKNGA- 238

  Fly   235 IAARKMSSAMSAAKAACDHMHDWWNGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNKQWKIV 299
             .:..:|.|.:.||.|        |....|......|......|||  :..|..:|.      ..
Yeast   239 -GSATLSMAHAGAKFA--------NAVLSGFKGERDVIEPSFVDSP--LFKSEGIEF------FA 286

  Fly   300 SGLTLSDFAKTKLSVTGKELQEEKDEAL----SVLDSNV 334
            |.:||......|:...| ||..|::|.|    ..|..|:
Yeast   287 SPVTLGPDGIEKIHPIG-ELSSEEEEMLQKCKETLKKNI 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_001285803.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	86/349 (25%)
		MDH_euk_cyt	6..328	CDD:130819	86/351 (25%)
MDH1	NP_012838.1	MDH_glyoxysomal_mitochondrial	18..331	CDD:133422	88/360 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810