Protein Alignment Mdh1 and mdh1b

DIOPT Version :10

• Sequence 1: NP_609394.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_009303919.1
• Gene: mdh1b / 767794
• ZFINID: ZDB-GENE-060929-384
• Length: 471
• Species: Danio rerio
• Alignment Length: 342
• Identity: 100/342 - (29%)
• Similarity: 165/342 - (48%)
• Gaps: 14/342 - (4%)

  Fly     4 PIRVVVTGAAGQIAYSLL-YMIARGEVFGKDQPIV-LHLLDIPPMVGVLEGVVMELADCALPLLV 66
            |:.:.::.|...:.|||: ::...|...|  .||. |||:|......:|:.:.||..|.|:|.|.
Zfish   131 PLHIWISSALNPVCYSLIPHLFTPGLFSG--LPIFSLHLMDTSGSEEMLQALKMETVDLAIPRLH 193

  Fly    67 EVVPTTDPAVGFKDVS-AAFLVGAMPRKEGMERKDLLSANVKIFRTQGQALDKFAKKDVKVLVVG 130
            ||...:|..:.|::.. ..||....|..|..:.::......:.|...||.::..|:|||:|||.|
Zfish   194 EVTIHSDQMLAFQEAHFIIFLDDQQPAGEYNDEQNDKDQVAEHFHRYGQLIETNAQKDVRVLVAG 258

  Fly   131 N-PANTNALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGVPISAVKNIIIWGNHSSTQYPD 194
            : ..|....:....||||...||.|||...:..|.:|:|.||.|..|.:.|:|:|||.|.:.:.|
Zfish   259 DFFINMKCSLLIENAPSIDPRNFVAMTTQLEYEARTQLAQKLSVKTSDITNVIVWGNISGSFHID 323

  Fly   195 AGQAKV--------TANGTVKSVVDAINDNGYLQGSFVETVQKRGAAVIAARKMSSAMSAAKAAC 251
            ..:|||        ..:|..:.|::.|.|..:|:..|...:.|..|.:.:....::|:|...|..
Zfish   324 LQRAKVFRYDGAIRGPDGFSQHVMEMIYDWKWLKTDFRSLLHKHRATISSKTNKATAISTTNAIL 388

  Fly   252 DHMHDWWNGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNKQWKIVSGLTLSDFAKTKLSVTG 316
            ..:..|.|..:|.:..|:||.|.|.:..|..::||.||...:..|.:.|.:.::|..:..|....
Zfish   389 AILKAWNNAESPEEVFSLGVLSTGQFGIPAGLVFSMPVSFTDGHWSVRSDVIVTDELRVNLDACA 453

  Fly   317 KELQEEKDEALSVLDSN 333
            .||:.|:|.|...|.::
Zfish   454 DELRMERDMAAKTLKND 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_609394.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	98/334 (29%)
mdh1b	XP_009303919.1	Rossmann-fold NAD(P)(+)-binding proteins	9..463	CDD:473865	98/333 (29%)