Protein Alignment Mdh1 and Mdh1b

DIOPT Version :9

• Sequence 1: NP_001285803.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_036010132.1
• Gene: Mdh1b / 76668
• MGIID: 1923918
• Length: 501
• Species: Mus musculus
• Alignment Length: 340
• Identity: 98/340 - (28%)
• Similarity: 164/340 - (48%)
• Gaps: 31/340 - (9%)

  Fly     1 MAEPIRVVVTGAAGQIAYSLLYMIARGEVFGKDQPIVLHLLDIPPMVGVLEGVVMELADCALPLL 65
            :..|::|.:..|...:...|:.::..|||||....|.|.|.|.......|..:|||..|.|.|:|
Mouse   128 LISPLQVWIASAGTYVCCHLIPLLLSGEVFGMHTEISLTLFDQEQREDCLRSIVMETQDLASPVL 192

  Fly    66 VEVVPTTDPAVGFKDVSAAFLVGAMPRKEGMERKDLLSANVKIFRTQGQALDKFAKKDVKVLVVG 130
            ..|...|.....|.......::.....:|....:..|.:.|.:.|..|..::|.|.|.|||:|.|
Mouse   193 RTVSFCTTVKEAFLQAQVIIILDDSTEEEVYSLESCLRSRVPLCRLYGYLIEKNAHKSVKVIVGG 257

  Fly   131 -NPANTNALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGVPISAVKNIIIWGNHSSTQYPD 194
             |..|....:...|||:| ..|..|:....:.:|.:.:|.|:....:.:|::|||||.:...|.|
Mouse   258 KNFVNLKTTLLMQYAPNI-ASNIIAVALGVEGQAKAVLARKMKTTSANIKDVIIWGNITGNNYVD 321

  Fly   195 AGQAKV-TANGTVK-------SVVDAINDNGYLQGSFVETVQ------KRGAAVIAARKMSSAMS 245
            ..:||| .....||       ||:..|.|..::...||:|::      |:...::||..:::.:.
Mouse   322 LRKAKVYNYESAVKGPPGHYHSVLSLIFDREWITKEFVQTLKILSSTGKQFGGILAAHSIATTLK 386

  Fly   246 AAKAACDHMHDWWNGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNKQWKIVSGL---TLSDF 307
            .          |::|:.||:.||:||.|:|.:|.|:.::||.||:.:|..|.:::.|   :||:
Mouse   387 Y----------WYHGSPPGEIVSLGVMSEGQFDIPEGIVFSMPVKFENGTWVVLTDLEDISLSE- 440

  Fly   308 AKTKLSVTGKELQEE 322
             ||...:||..:||:
Mouse   441 -KTLSRLTGDLIQEK 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_001285803.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	98/338 (29%)
		MDH_euk_cyt	6..328	CDD:130819	97/335 (29%)
Mdh1b	XP_036010132.1	NADB_Rossmann	9..459	CDD:419666	98/340 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849615
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740