Protein Alignment Mdh1 and mdh2

DIOPT Version :9

• Sequence 1: NP_001285803.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_998296.1
• Gene: mdh2 / 406405
• ZFINID: ZDB-GENE-040426-2143
• Length: 337
• Species: Danio rerio
• Alignment Length: 287
• Identity: 66/287 - (22%)
• Similarity: 106/287 - (36%)
• Gaps: 98/287 - (34%)

  Fly     6 RVVVTGAAGQIAYSLLYMIARGEVFGKDQPIV--LHLLDIPPMVGV------------LEGVV-- 54
            :|.|.||:|.|...|..::       |:.|:|  |.|.||....||            ::|.:
Zfish    25 KVAVLGASGGIGQPLSLLL-------KNSPLVSELSLFDIAHTPGVAADLSHIETRAHVKGYIGA 82

  Fly    55 MELADCALPLLVEVVPTTDPAVGFKDVSAAFLVGAMPRKEGMERKDLLSANVKIFRTQGQALDKF 119
            .:|.|......|.|:|                 ..:|||.||.|.||.:.|..|..|   .:|..
Zfish    83 DQLGDALKGCEVVVIP-----------------AGVPRKPGMTRDDLFNTNATIVAT---LVDGC 127

  Fly   120 AK--KDVKVLVVGNPANTNALVCSS-------YAPSIPRENFSAMTRLDQNRATSQIAAKLGVPI 175
            |:  ....:.::.||.|:...:.|.       |.|:    ....:|.||..||.:.:|...|:..
Zfish   128 ARHCPQAMICIISNPVNSTIPITSEVMKKHGVYNPN----KIFGVTTLDIVRANTFVAELKGLDP 188

  Fly   176 SAVKNIIIWGNHS-------------STQYP------------DAGQAKVTA-----NGTVK--- 207
            :.| |:.:.|.|:             ..::|            :||...|.|     :.|:.
Zfish   189 ARV-NVPVVGGHAGITIIPLISQCTPKVEFPADQLSALTGRIQEAGTEVVKAKAGAGSATLSMAY 252

  Fly   208 -------SVVDAIN-DNGYLQGSFVET 226
                   |::||:| ..|.::.|||.:
Zfish   253 AGARFTFSLLDAMNGKEGVVECSFVRS 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_001285803.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	66/287 (23%)
		MDH_euk_cyt	6..328	CDD:130819	66/287 (23%)
mdh2	NP_998296.1	PLN00106	6..328	CDD:215058	66/287 (23%)
		MDH_glyoxysomal_mitochondrial	25..333	CDD:133422	66/287 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810