Protein Alignment Mdh1 and ldha

DIOPT Version :10

• Sequence 1: NP_609394.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_571321.1
• Gene: ldha / 30496
• ZFINID: ZDB-GENE-991026-5
• Length: 333
• Species: Danio rerio
• Alignment Length: 343
• Identity: 80/343 - (23%)
• Similarity: 131/343 - (38%)
• Gaps: 69/343 - (20%)

  Fly     5 IRVVVTGAAGQIAYSLLYMIARGEVFGKDQPIVLHLLDIPPMVGVLEGVVMELADCALPLLV-EV 68
            :.||..|..|        |.|...:..||....|.|:|:  |...|:|..|:|...:|.|.. ::
Zfish    24 VTVVGVGMVG--------MAAAVSILLKDLTDELALVDV--MEDKLKGEAMDLQHGSLFLKTHKI 78

  Fly    69 VPTTDPAVGFKDVSAAFLVGAMPRKEGMERKDLLSANVKIFRTQGQALDKFAKKDVKVLVVGNPA 133
            |...|.:|...........||. ::||..|.:|:..||.||:.....:.|::...: :|||.||.
Zfish    79 VADKDYSVTANSKVVVVTAGAR-QQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCI-LLVVSNPV 141

  Fly   134 NTNALVCSSYAPSIPREN-FSAMTRLDQNRATSQIAAKLGVPISAVKNIIIWGNHSSTQYP---- 193
            :....|....: .:||.. ..:.|.||..|....:..|||:..|:....:: |.|..:..|
Zfish   142 DILTYVAWKLS-GLPRNRVIGSGTNLDSARFRYLMGEKLGIHPSSCHGWVV-GEHGDSSVPVWSG 204

  Fly   194 --DAGQAKVTAN---GT------VKSVVDAINDNGYLQGSFVETVQKRGAAVIAARKMSSAMSAA 247
              .||.:....|   ||      .|||...:.|:.|      |.::.:|..     ..:..||.|
Zfish   205 VNVAGVSLQALNPDLGTDKDKEDWKSVHKMVVDSAY------EVIKLKGYT-----SWAIGMSVA 258

  Fly   248 ---KAACDHMHDWWNGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNKQWKIVSGLTLSDFAK 309
               ::...:||         :...:.....|.:...::|..|.|..:.|      :|||
Zfish   259 DLCESILKNMH---------KCHPVSTLVKGMHGVNEEVFLSVPCILGN------NGLT------ 302

  Fly   310 TKLSVTGKELQEEKDEAL 327
               .|....|:.|:::.|
Zfish   303 ---DVVHMTLKPEEEKQL 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_609394.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	79/341 (23%)
ldha	NP_571321.1	LDH_1	19..330	CDD:133429	80/343 (23%)