Protein Alignment Mdh1 and Ldha

DIOPT Version :9

• Sequence 1: NP_001285803.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_006229294.1
• Gene: Ldha / 24533
• RGDID: 2996
• Length: 361
• Species: Rattus norvegicus
• Alignment Length: 356
• Identity: 77/356 - (21%)
• Similarity: 122/356 - (34%)
• Gaps: 87/356 - (24%)

  Fly     5 IRVVVTGAAGQ-IAYSLLYMIARGEVFGKDQPIVLHLLDIPPMVGVLEGVVMELADCALPLLV-E 67
            |.||..||.|. .|.|:|.         ||....|.|:|:  :...|:|.:|:|...:|.|.. :
  Rat    52 ITVVGVGAVGMACAISILM---------KDLADELALVDV--IEDKLKGEMMDLQHGSLFLKTPK 105

  Fly    68 VVPTTDPAVGFKDVSAAFLVGAMPRKEGMERKDLLSANVKIFRTQGQALDKFAKKDVKVLVVGNP 132
            :|.:.|.:|...........||. ::||..|.:|:..||.||:.....:.|::.: .|:|:|.||
  Rat   106 IVSSKDYSVTANSKLVIITAGAR-QQEGESRLNLVQRNVNIFKFIIPNVVKYSPQ-CKLLIVSNP 168

  Fly   133 ANTNALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGV-PISAVKNIIIWGNHSSTQYP--- 193
            .:....|....:.........:...||..|....:..:||| |:|....::  |.|..:..|
  Rat   169 VDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVL--GEHGDSSVPVWS 231

  Fly   194 --------------------DAGQAKVTANGTVKSVVDAINDNGYLQ-------GSFVETVQKRG 231
                                |..|.|......|.|..:.|...||..       ....|::.|.
  Rat   232 GVNVAGVSLKSLNPQLGTDADKEQWKDVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKN- 295

  Fly   232 AAVIAARKMSSAMSAAKAACDHMHDWWNGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNKQW 296
                 .|::....:..|                          |.|...:||..|.|..:.....
  Rat   296 -----LRRVHPISTMIK--------------------------GLYGIKEDVFLSVPCILGQNGI 329

  Fly   297 KIVSGLTLSDFAKTKLSVTG-------KELQ 320
            ..|..:||:...:.:|..:.       ||||
  Rat   330 SDVVKVTLTPDEEARLKKSADTLWGIQKELQ 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_001285803.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	77/356 (22%)
		MDH_euk_cyt	6..328	CDD:130819	76/355 (21%)
Ldha	XP_006229294.1	LDH_1	48..358	CDD:133429	73/352 (21%)
		L-LDH-NAD	54..353	CDD:273796	72/345 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810