Protein Alignment Mdh1 and mdh-2

DIOPT Version :9

• Sequence 1: NP_001285803.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_498457.1
• Gene: mdh-2 / 175936
• WormBaseID: WBGene00003162
• Length: 341
• Species: Caenorhabditis elegans
• Alignment Length: 354
• Identity: 79/354 - (22%)
• Similarity: 137/354 - (38%)
• Gaps: 68/354 - (19%)

  Fly     6 RVVVTGAAGQIAYSLLYMIARGEVFGKDQPIVLHL-----LDIPPMVGVLEGVVMELADCALPLL 65
            :|.:.||||.|...|..::       |..|:|.||     ::.|       ||..:|:.  :...
 Worm    30 KVALLGAAGGIGQPLGLLL-------KQDPLVAHLALYDVVNTP-------GVAADLSH--IDSN 78

  Fly    66 VEVVPTTDPAVGFKDVSAAFLV---GAMPRKEGMERKDLLSANVKIFRTQGQALDKFAKKDVKVL 127
            .:|...|.|...:..|..|.::   ..:|||.||.|.||.:.|..|.|.....:.|.:.|.: :.
 Worm    79 AKVTAHTGPKELYAAVENADVIVIPAGVPRKPGMTRDDLFNTNAGIVRDLAAVIAKASPKAL-IA 142

  Fly   128 VVGNPANTNALVCSSYAPSI----PRENFSAMTRLDQNRATSQIAAKLGVPISAVKNIIIWGNHS 188
            ::.||.|:...:.|......    |:..| .:|.||..|:.:.::...|...|.....::.|:..
 Worm   143 IITNPVNSTVPIASEVLKKAGVYDPKRVF-GVTTLDVVRSQAFVSELKGHDASKTVVPVVGGHAG 206

  Fly   189 STQYPDAGQAKVT---ANGTVKSVVDAINDNGYLQGSFVETVQKRGAAVIAARKMSSAMSAAKAA 250
            .|..|...|.|.:   :...:..:...|.|.|      .|.|..:..|  .:..:|.|::.|:.|
 Worm   207 ITIIPLLSQVKPSTKFSEEEISKLTPRIQDAG------TEVVNAKAGA--GSATLSMALAGARFA 263

  Fly   251 CDHMHDWWNGTAPG---------QFVSMGVFSDGSYDSPKDV-IFSFPVEI-KNKQWKIVSGLTL 304
                    |....|         .:|:.        |:.|.| .||.|||: .|...||:....:
 Worm   264 --------NALVRGIKGEKNVQCAYVAS--------DAVKGVEYFSTPVELGPNGVEKILGVGKV 312

  Fly   305 SDFAKTKLSVTGKELQEEKDEALSVLDSN 333
            |.:.:..:..:..||.:...:.::.:..|
 Worm   313 SAYEQKLIDASVPELNKNIAKGVAFVKGN 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_001285803.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	78/346 (23%)
		MDH_euk_cyt	6..328	CDD:130819	78/347 (22%)
mdh-2	NP_498457.1	PLN00106	15..333	CDD:215058	78/344 (23%)
		MDH_glyoxysomal_mitochondrial	30..338	CDD:133422	78/349 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810