Protein Alignment Mdh1 and Mdh2

DIOPT Version :10

• Sequence 1: NP_609394.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_032643.2
• Gene: Mdh2 / 17448
• MGIID: 97050
• Length: 338
• Species: Mus musculus
• Alignment Length: 281
• Identity: 70/281 - (24%)
• Similarity: 105/281 - (37%)
• Gaps: 86/281 - (30%)

  Fly     6 RVVVTGAAGQIAYSLLYMIARGEVFGKDQPIV--LHLLDIPPMVGV------------LEGVV-- 54
            :|.|.||:|.|...|..::       |:.|:|  |.|.||....||            ::|.:
Mouse    26 KVAVLGASGGIGQPLSLLL-------KNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGP 83

  Fly    55 MELADCALPLLVEVVPTTDPAVGFKDVSAAFLVGAMPRKEGMERKDLLSANVKIFRTQGQALDKF 119
            .:|.||.....|.|:|                 ..:|||.||.|.||.:.|..|..|...|..:.
Mouse    84 EQLPDCLKGCDVVVIP-----------------AGVPRKPGMTRDDLFNTNATIVATLTAACAQH 131

  Fly   120 AKKDVKVLVVGNPANT----NALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGVPISAVKN 180
            . .:..|.::.||.|:    .|.|...:....|.:.| .:|.||..||.:.:|...|:..:.|..
Mouse   132 C-PEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIF-GVTTLDIVRANTFVAELKGLDPARVNV 194

  Fly   181 IIIWGNHSSTQYP------------------------DAG----QAKVTANGT-----------V 206
            .:|.|:...|..|                        :||    :||..|...           |
Mouse   195 PVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFV 259

  Fly   207 KSVVDAIN-DNGYLQGSFVET 226
            .|:|||:| ..|.::.|||::
Mouse   260 FSLVDAMNGKEGVVECSFVQS 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_609394.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	70/281 (25%)
Mdh2	NP_032643.2	MDH_glyoxysomal_mitochondrial	26..334	CDD:133422	70/281 (25%)