Protein Alignment Mdh1 and Ldha

DIOPT Version :9

• Sequence 1: NP_001285803.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_001129541.2
• Gene: Ldha / 16828
• MGIID: 96759
• Length: 361
• Species: Mus musculus
• Alignment Length: 355
• Identity: 76/355 - (21%)
• Similarity: 118/355 - (33%)
• Gaps: 85/355 - (23%)

  Fly     5 IRVVVTGAAGQ-IAYSLLYMIARGEVFGKDQPIVLHLLDIPPMVGVLEGVVMELADCALPLLV-E 67
            |.||..||.|. .|.|:|.         ||....|.|:|:  |...|:|.:|:|...:|.|.. :
Mouse    52 ITVVGVGAVGMACAISILM---------KDLADELALVDV--MEDKLKGEMMDLQHGSLFLKTPK 105

  Fly    68 VVPTTDPAVGFKDVSAAFLVGAMPRKEGMERKDLLSANVKIFRTQGQALDKFAKKDVKVLVVGNP 132
            :|.:.|..|...........||. ::||..|.:|:..||.||:.....:.|:: ...|:|:|.||
Mouse   106 IVSSKDYCVTANSKLVIITAGAR-QQEGESRLNLVQRNVNIFKFIIPNIVKYS-PHCKLLIVSNP 168

  Fly   133 ANTNALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGVPISAVKNIIIWGNHSSTQYP---- 193
            .:....|....:.........:...||..|....:..:|||...:....:: |.|..:..|
Mouse   169 VDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWVL-GEHGDSSVPVWSG 232

  Fly   194 -------------------DAGQAKVTANGTVKSVVDAINDNGYLQ-------GSFVETVQKRGA 232
                               |..|.|......|.|..:.|...||..       ....|::.|.
Mouse   233 VNVAGVSLKSLNPELGTDADKEQWKEVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKN-- 295

  Fly   233 AVIAARKMSSAMSAAKAACDHMHDWWNGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNKQWK 297
                .|::....:..|                          |.|...:||..|.|..:......
Mouse   296 ----LRRVHPISTMIK--------------------------GLYGINEDVFLSVPCILGQNGIS 330

  Fly   298 IVSGLTLSDFAKTKLSVTG-------KELQ 320
            .|..:||:...:.:|..:.       ||||
Mouse   331 DVVKVTLTPEEEARLKKSADTLWGIQKELQ 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_001285803.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	76/355 (21%)
		MDH_euk_cyt	6..328	CDD:130819	75/354 (21%)
Ldha	NP_001129541.2	LDH_1	48..358	CDD:133429	72/351 (21%)
		L-LDH-NAD	54..353	CDD:273796	71/344 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910