Protein Alignment Mdh1 and Ldhal6b

DIOPT Version :9

• Sequence 1: NP_001285803.1
• Gene: Mdh1 / 34414
• FlyBaseID: FBgn0262782
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_780558.1
• Gene: Ldhal6b / 106557
• MGIID: 2146830
• Length: 382
• Species: Mus musculus
• Alignment Length: 317
• Identity: 65/317 - (20%)
• Similarity: 116/317 - (36%)
• Gaps: 84/317 - (26%)

  Fly     5 IRVVVTGAAGQIAYSLLYMIARGEVFGKDQPIVLHLLDIPPMVG----VLEGVVMELADCALPL- 64
            :.:|.||:.|...  .:.:||:|            |.|...:|.    .::|..|:|...::.:
Mouse    73 VSIVGTGSVGMAC--AIGIIAKG------------LTDELALVDNNEEKMKGETMDLQHGSVFMK 123

  Fly    65 LVEVVPTTDPAVGFKDVSAAFLVGAMPRKEGME-RKDLLSANVKIFRTQGQALDKFAKKDVKVLV 128
            :..:|.:.|..|...  |...::.|..|:|..| |.:|:..||.||:.....:.|.:.: .|::|
Mouse   124 MPNIVCSKDFRVTAN--SEVVIITAGARQEKNETRLNLVQRNVTIFKAMVAEIIKHSPR-CKIIV 185

  Fly   129 VGNPANTNALVCSSYAPSIPRENFSAMTRLDQNRATSQIAAKLGVPISAVKNIIIWGNHSSTQYP 193
            |.||.:....|....:.........:...||..|....:..:||:...:....:: |.|..:..|
Mouse   186 VSNPVDILTFVTWKLSGFPKNRIIGSGCNLDTARFRYMLGQRLGIHSESCHGWVL-GEHGDSSVP 249

  Fly   194 DAGQAKVTANGTVKSVVDAINDNGYLQGSFVETVQKRGAAVIAARKMSSAMSAAKAACDHMHDWW 258
                           |...:|..|                 :..|:::||:..:|..     :.|
Mouse   250 ---------------VWSGVNIAG-----------------VPLRELNSAIGTSKDP-----EKW 277

  Fly   259 NGTAPGQFVSMGVFSDGSYDSPKDVIFSFPVEIKNK---QWKIVSGLTLSDFAKTKL 312
            .                  |..|:||.|....||.|   .|.|  ||:::|.|::.|
Mouse   278 G------------------DVHKEVIASAYNIIKMKGYTSWAI--GLSVTDIAESIL 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdh1	NP_001285803.1	MDH_cytoplasmic_cytosolic	3..327	CDD:133421	65/317 (21%)
		MDH_euk_cyt	6..328	CDD:130819	65/316 (21%)
Ldhal6b	NP_780558.1	LDH_1	70..379	CDD:133429	65/317 (21%)
		L-LDH-NAD	75..375	CDD:273796	65/315 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810