Protein Alignment da and tcf3a

DIOPT Version :10

• Sequence 1: NP_001356956.1
• Gene: da / 34413
• FlyBaseID: FBgn0267821
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_001428327.1
• Gene: tcf3a / 30310
• ZFINID: ZDB-GENE-990415-51
• Length: 584
• Species: Danio rerio
• Alignment Length: 690
• Identity: 205/690 - (29%)
• Similarity: 278/690 - (40%)
• Gaps: 201/690 - (29%)

  Fly    27 PTGTVGA-DRGGGGGY----HSP------YGSLGVENGMYPSDFNSMHDTVNGGNNRYANASTVD 80
            |:...|. ||.|.|.:    :||      ||    :...||...|..:..::|.:.|
Zfish    35 PSSQFGLDDRNGSGSWGSEANSPSFGARLYG----DGHHYPEHDNMYNLEIDGKSER-------- 87

  Fly    81 QYFDSAAAGSGGAWCQPQM---------SSANSYMGQSAYQNSGPLSGH-------SIDQQQQQV 129
                      |....|||:         |.|.|..|...  :|...|.|       |||...::.
Zfish    88 ----------GYPVTQPQLLPGEINIAASDALSPPGMKG--SSQFYSPHRRRPAESSIDPLPKKR 140

  Fly   130 HQADGLGMGGGGGGGVGADGMHCPVTTGLPPISSFRPTSGGIGGPGAGQQAPVNVNVN------- 187
            ....||..      .:.|    .|.:||    ..:...|.|..|...|...|...||.
Zfish   141 KVPHGLPT------SISA----YPGSTG----DDYNQDSAGYPGSKPGNLYPGFFNVQEGLPDHW 191

  Fly   188 -----PPAVFN--SPQAHNHNHTVQAQHSALSTAGPLGHHSLNHTPHAHSHTLPLP-HALPHGHT 244
                 ||.:.|  :||...                ||.....|:..|.....||.. |::|.|:.
Zfish   192 GQSGYPPVMSNFINPQKRQ----------------PLPVSPQNYPLHGSEVNLPSSFHSVPAGYG 240

  Fly   245 LPHPHHSQQNSPAVQSSDAFSG-AGASVKVAGAGNSSAAALRQQMYMPADQSISSFGSNPSTPVN 308
            :|:      ::|.:.||:...| .||:...:||....|.|   .:| |:|.:.|:|.|.|||||.
Zfish   241 VPN------HTPPISSSEGIMGNRGANAGSSGAEIGKALA---SIY-PSDNNGSNFSSTPSTPVG 295

  Fly   309 SPPPLTQSVVGGGGEPSVSGGSGWGHSVLNGGPSSSYASEMVPVSSLHTMASVFQGVRMEERLDD 373
            ||..:..|            .|.|........||..:.            |.:.|. ::::||.:
Zfish   296 SPSNVAAS------------ASQWPKGSSQPAPSPGFE------------AGLAQS-KLDDRLGE 335

  Fly   374 ALNVLRNHCEPEMLAGVN-QSLASIDNIDALTSFVPNSPSHLGSGGNSGSVSNTSNAALVHEVLA 437
            ||:|||||.     .|.: |||.|.    |:            ||.::|
Zfish   336 ALHVLRNHA-----VGTDMQSLLSA----AI------------SGHSAG---------------- 363

  Fly   438 LGAAAAAGTSGQSVGGAGSLASLKLDRSA-STSLPKQTKKRKEHTAISNSVPAGVSTTSSLTSLD 501
               |||.|:..|:.|.|..|..|..:.|. :..||:.:...:.|.......|:..|.|  .|||.
Zfish   364 ---AAALGSLSQAFGLANRLPGLMSNHSEDAAGLPQSSALLQGHHTSHQPPPSSQSDT--FTSLS 423

  Fly   502 I--------SDTKPTSSIESSNSGLQQHSQGKGTKRPRRYCSSADEDDDAEP-----AVKAIREK 553
            :        ||.|.....:..|..:...|:.:......|..:|.|||:|.:.     .|||.||:
Zfish   424 LARSSHASSSDIKREDKDDDENLSIADKSEDEKKDGKSRTRTSQDEDEDEDDEDLPVEVKAERER 488

  Fly   554 ERRQANNARERIRIRDINEALKELGRMCMTHLKSDKPQTKLGILNMAVEVIMTLEQQVRERNLNP 618
            |||.|||||||:|:||||||.|||||||..||.::||||||.||:.||.||:.||||||||||||
Zfish   489 ERRMANNARERLRVRDINEAFKELGRMCQLHLSNEKPQTKLLILHQAVNVILNLEQQVRERNLNP 553

  Fly   619 KAACLKRREEEKAEDGPKLSAQHHMIPQPQQVGGTPGSSY 658
            ||||||||||||            :..:.|.:.|..|..:
Zfish   554 KAACLKRREEEK------------VTGEAQMLSGLGGDGH 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
da	NP_001356956.1	bHLH_E-protein_Da_like	554..623	CDD:381473	53/68 (78%)
tcf3a	NP_001428327.1	None