Protein Alignment da and hlh-30

DIOPT Version :9

• Sequence 1: NP_001356956.1
• Gene: da / 34413
• FlyBaseID: FBgn0267821
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_001023411.1
• Gene: hlh-30 / 177157
• WormBaseID: WBGene00020930
• Length: 524
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 127/595 - (21%)
• Similarity: 195/595 - (32%)
• Gaps: 161/595 - (27%)

  Fly   240 PHGHTLPHPHHSQQNSPAVQS--SDAFSGAGASVKVAGAGNSSAAALRQQMYMPADQSISSFGSN 302
            |.....|.....||...|.|.  .|....|.||....|||.|..........:|..|  .|.||.
 Worm    19 PRAQQPPGAQQQQQPQQAQQQFYDDEPYQANASQFRFGAGKSMEQRRETGNLIPIAQ--RSMGST 81

  Fly   303 PSTPVNSPPPLTQSVVGGGGEPSVSGGSGWG--------HSVL-------NGGPSSSYASEMVPV 352
             |||..|.|  |||..|||     |.|:...        |.:|       .|.|.|..:.::...
 Worm    82 -STPFGSAP--TQSYFGGG-----SSGAALSSPRKMQQTHQMLFGNIQPPRGSPPSDGSDKIHRF 138

  Fly   353 SSLHT---MASVFQGVRMEERLDDALNVLRNHCEPEMLAGVNQSLA-SIDNIDALTSFVPNSPSH 413
            ....|   :..|| |..:::.:.|.|..:.:  :..|..|..:.:. ..:...::...:|.:.|.
 Worm   139 GESPTPGGVGGVF-GTELDDLIIDELMGMED--DQRMRPGATRPMTIGGEKTMSMARPIPGASSR 200

  Fly   414 LGSGGNSGSVSNTSNAALVHEVLALGAAAAAGTSGQSVGGAGSLASLKLDRSASTSLPKQTKKRK 478
            .|| |:|||.....|
 Worm   201 AGS-GHSGSPITIPN-------------------------------------------------- 214

  Fly   479 EHTAISNSVPAGVSTTSSLTSLDISDTKPTSSIESSNSGLQQHSQGKGTKRPRRYCSSADEDDDA 543
               |:||:....||:::..:|:||.......|....|||        |...|..|
 Worm   215 ---AMSNNFRQVVSSSAPTSSIDIEKMIGAVSNGGGNSG--------GDNDPEDY---------- 258

  Fly   544 EPAVKAIREKERRQANNARERIRIRDINEALKELGRMCMTHLKSDKPQTKLGILNMAVEVIMTL- 607
                  .|::.::..:|..||.|..:||:.:||||:|...:...|....|..||..:.:.|..|
 Worm   259 ------YRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKNTSEDMKLNKGTILKASCDYIRVLQ 317

  Fly   608 -----------EQQVRERNLNPKAACLKRREEEKAEDGPKLSAQH-----HMIPQP--QQV---- 650
                       :|:..|...:..|..:|..||..|..|.::...|     .:|.:|  |::
 Worm   318 KDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQGVQVPPSHLPPIPKVIERPIKQEIDESP 382

  Fly   651 -GGTPGSSYHSQPAQLVPPSSQT----ISTMTISLPVNQANNGLPPHLQQQQQQQSQLGHAQLPQ 710
             ..||..|:.|....|...::.|    |::...|.|.|..||..|      ......:|.|..|.
 Worm   383 PNHTPTGSFVSSSGFLSEVTNNTAAMQITSPNDSRPNNFMNNSAP------SDSFFSVGSASPPD 441

  Fly   711 XHAPPRNPFWK--SSSSLSSIKTE----------CIEGSAAKYSDNLELENQVLSNMFWRCRPPK 763
             ........||  .|::.|.:..:          .|..:.|..|.:.. .:|:..::.|..  ..
 Worm   442 YRTSSGTASWKLPGSNAFSDLMMDDLNPMMNGDPLISSAGAHPSPHFH-SSQMSPDIHWDA--SG 503

  Fly   764 LQPQPLQNVQ 773
            ..|.|:...|
 Worm   504 FSPDPINTQQ 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
da	NP_001356956.1	HLH	560..613	CDD:197674	18/64 (28%)
hlh-30	NP_001023411.1	bHLHzip_MITF_like	260..328	CDD:381403	18/67 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910