Protein Alignment da and hlh-2

DIOPT Version :9

• Sequence 1: NP_001356956.1
• Gene: da / 34413
• FlyBaseID: FBgn0267821
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_001021581.1
• Gene: hlh-2 / 172458
• WormBaseID: WBGene00001949
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 117/443 - (26%)
• Similarity: 188/443 - (42%)
• Gaps: 104/443 - (23%)

  Fly   226 PHAHSH-------TLPLPHALPHGHTLPHPHHSQQNSPAVQSSDAF------SGAGASVKVAGAG 277
            |:|:.:       |:.:|......|..|:|   ...:..:..|.||      :...|||   .|.
 Worm    27 PNAYDYPYNIDPTTIQMPDYWSGYHLNPYP---PMQTTDIDYSSAFLPTHPPTETPASV---AAP 85

  Fly   278 NSSAAALRQQMYMPADQSISSFGSNPSTPVNSPPPL-TQSVVGGGGEPSVSGGSGWGHSVLNGGP 341
            .|:.:.::     |...:.|:..:.|||   :|.|. |..|:......:.:..|....:::...|
 Worm    86 TSATSDIK-----PIHATSSTSTTAPST---APAPTSTTDVLELKPTTAPATNSAETSAIVAPQP 142

  Fly   342 SSSYASEMVPVSSLHTMASVFQGV---RMEERLDDALNVLRNHCEPEMLAGVNQSLASIDNIDAL 403
            .::..:.:..:||::|....:.|.   ..:.:..:|:|...: ..|....|.:.|:|...:....
 Worm   143 LTNLTAPIDAMSSMYTWPQTYPGYLPPSEDNKASEAVNPYIS-IPPTYTFGADPSVADFSSYQQQ 206

  Fly   404 TSFVPNSPSHLGSGGNSGSVSNTSNAALVHEVLALGAA------AAAGTSGQSVGGAGSLASLKL 462
            .:..||     |.||::..|...      |:....|.:      ...|.:|...|.:.|  |::.
 Worm   207 LAGQPN-----GLGGDTNLVDYN------HQFPPAGMSPHFDPNGYPGMTGMPPGSSAS--SVRN 258

  Fly   463 DRSASTSLPKQTKKRKEHTAISNSVPAGVSTTSSLTSLDISDTKPTSSIESSNSGLQQHSQGKGT 527
            |:|||    :.|.:|:.....|:.:|...|::|.|               |.|..:
 Worm   259 DKSAS----RATSRRRVQGPPSSGIPTRHSSSSRL---------------SDNESM--------- 295

  Fly   528 KRPRRYCSSADEDDDAEPAVKAIREKERRQANNARERIRIRDINEALKELGRMCMTH-LKSDKPQ 591
                    |.|:|.|            ||..||||||:|:||||.|.|||||||..| ..:::.|
 Worm   296 --------SDDKDTD------------RRSQNNARERVRVRDINSAFKELGRMCTQHNQNTERNQ 340

  Fly   592 TKLGILNMAVEVIMTLEQQVRERNLNPKA-ACLKRREEE---KAEDGPKLSAQ 640
            ||||||:.||.||..||:|||:||:|||. |.:||:.::   |..|....|||
 Worm   341 TKLGILHNAVSVITQLEEQVRQRNMNPKVMAGMKRKPDDDKMKMLDDNAPSAQ 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
da	NP_001356956.1	HLH	560..613	CDD:197674	34/53 (64%)
hlh-2	NP_001021581.1	bHLH_E-protein_E47-like	297..368	CDD:381513	44/82 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159476
Domainoid	1	1.000	66	1.000	Domainoid score	I6570
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001459
OrthoInspector	1	1.000	-	-		oto19912
orthoMCL	1	0.900	-	-		OOG6_105744
Panther	1	1.100	-	-	LDO	PTHR11793
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4532
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.960