Protein Alignment da and tcf3

DIOPT Version :9

• Sequence 1: NP_001356956.1
• Gene: da / 34413
• FlyBaseID: FBgn0267821
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: XP_031753734.1
• Gene: tcf3 / 100101779
• XenbaseID: XB-GENE-478265
• Length: 706
• Species: Xenopus tropicalis
• Alignment Length: 639
• Identity: 180/639 - (28%)
• Similarity: 253/639 - (39%)
• Gaps: 178/639 - (27%)

  Fly    28 TGTVGADRGGGGGYHSPYGSLGVENGM-------YPSDF---------------NSMHDTVNGGN 70
            :|.||.:.      ..||.:.|.::||       .|.|.               .|.:.|....:
 Frog   101 SGLVGKNE------RPPYSTFGRDSGMAMNQTGFLPGDLAMNSPSALSPNAGKAGSQYYTYPNNS 159

  Fly    71 NRYANASTVDQYFDSA----------------AAGSGGAWCQPQMSSANSYMGQSAYQNSGPLSG 119
            .|....|.:.:..|:.                .|.||..:|..:.|.||.....|.|.
 Frog   160 RRRPGDSNLGKKTDAQPKKVRKVPPGLPSSVYPANSGDEYCGDRGSYANPKAPNSVYP------- 217

  Fly   120 HSIDQQQQQVHQADGLGMGGGGGGGVGADGMHCPVTTGLPPISSFRPTSGGIGGPGAGQQAPVNV 184
                                  |.....||:|..        |....:|||||..|..
 Frog   218 ----------------------GAFYMTDGLHSS--------SDIWASSGGIGQGGYS------- 245

  Fly   185 NVNPPAVFNSPQAHNHNHTVQAQHSALSTAGPLGHHSLNHTPH------AHSHTLPLPHALPHGH 243
                 :|.||.|:              |.:...|..||:  ||      .||..:. |.......
 Frog   246 -----SVLNSSQS--------------SVSQTTGFSSLH--PHERMGFPMHSGEVN-PSVTSSFS 288

  Fly   244 TLPHPHHSQQNSPAVQSSDAFSGAGASVKVAGAGNSSAAALRQQMYMPADQSISSFGSNPSTPVN 308
            |.|..:....::|.:.|.|...| ........:|::...|| ..:|.| |.|.::|.|.|||||.
 Frog   289 TTPAQYGVSSHTPPISSGDTMIG-NRGTATGSSGDALGKAL-ASIYSP-DHSSTNFSSTPSTPVG 350

  Fly   309 SPPPLTQSVVGGGGEPSVSGGSGWGHSVLNGGPSSSYASEMVPVSSLHTMASVFQGVRMEERLDD 373
            ||    |.:.|.|..|..||         .|..|.||.      .:|||:.:     :||:|||:
 Frog   351 SP----QGITGSGQWPRASG---------PGALSPSYD------GTLHTLQN-----KMEDRLDE 391

  Fly   374 ALNVLRNHC--EPEMLAGVNQSLASIDNIDALTSFVPNSPSHLGSGGNSG--SVSNTSNAALVHE 434
            |::|||:|.  :...|.|.::.:.|:.:..|         |.||||..:.  |::|..:....|.
 Frog   392 AIHVLRSHAVGQTGSLPGGHEDIHSLLSATA---------SVLGSGFPAAVLSLANRHSMLNSHT 447

  Fly   435 VLALGAAAAAGTSGQSV-GGAGSLASLKLDRSASTSLPKQTKKRKEHTAISNSVPAGVSTTSSLT 498
            ..||.:|:....|..:| ...|||..|...:.:.:.||          .:..:||.|.:......
 Frog   448 EEALPSASNMLHSQVTVPAQPGSLPDLTRPQDSYSGLP----------GLGRAVPPGRAPEIKRE 502

  Fly   499 SLDISDTKPTSSIESSNSGLQQHSQGKGTKRPRRYCS-----SADEDDDAEPAVKAIREKERRQA 558
            |.:..:.:....:..     .:..:.| |:|.|..||     ..:|||:..|..||.||||||.|
 Frog   503 SKEDEENRSVGDLSD-----DEKKESK-TQRSRTRCSINSQDEDEEDDNLPPEQKAEREKERRVA 561

  Fly   559 NNARERIRIRDINEALKELGRMCMTHLKSDKPQTKLGILNMAVEVIMTLEQQVR 612
            ||||||:|:||||||.|||||||..||.|:||||||.||:.||.||::||||||
 Frog   562 NNARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILSLEQQVR 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
da	NP_001356956.1	HLH	560..613	CDD:197674	40/53 (75%)
tcf3	XP_031753734.1	bHLH_SF	557..617	CDD:412148	45/59 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I8128
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3593
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D260626at33208
OrthoFinder	1	1.000	-	-		FOG0001459
OrthoInspector	1	1.000	-	-		otm47878
Panther	1	1.100	-	-	O	PTHR11793
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1175
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160