DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS7 and MRPS7

DIOPT Version :9

Sequence 1:	NP_001260339.1	Gene:	mRpS7 / 34412	FlyBaseID:	FBgn0032236	Length:	218	Species:	Drosophila melanogaster
Sequence 2:	NP_057055.2	Gene:	MRPS7 / 51081	HGNCID:	14499	Length:	242	Species:	Homo sapiens

Alignment Length:	207	Identity:	84/207 - (40%)
Similarity:	127/207 - (61%)	Gaps:	10/207 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SVYPTHYVEPIVQK--YKQ-----LEQKNDLSKLYHVP-IKAAVNKSSDTIFHDDTKHKMINYIT 77
            |.|...:.:|::.|  |::     .|::..:.:|.... ||||....:.::|.|....|..|.:.
Human    35 SRYSPEFKDPLIDKEYYRKPVEELTEEEKYVRELKKTQLIKAAPAGKTSSVFEDPVISKFTNMMM 99

  Fly    78 KKGNSALARTLLSKTLELIKRTQTEHMNLAKG-EKTTINTNPETLLKQAVENCRPLLQVTAIKRG 141
            ..||..|||:|:.:|||.:||.|.|..:.|.. |:.||..||.|:..||::||.|::.:..|.:|
Human   100 IGGNKVLARSLMIQTLEAVKRKQFEKYHAASAEEQATIERNPYTIFHQALKNCEPMIGLVPILKG 164

  Fly   142 GVTYQVPVPITTKRSYFLAMKWLLEAAREKE-RKVSLPEKLAWEILDAAHGQGRVIKRKDDLHRL 205
            |..||||||:..:|..||||||::...|:|: ::..:||||:.::|:|.|.||.|||||.|||::
Human   165 GRFYQVPVPLPDRRRRFLAMKWMITECRDKKHQRTLMPEKLSHKLLEAFHNQGPVIKRKHDLHKM 229

  Fly   206 CESNRAYAHYRW 217
            .|:|||.|||||
Human   230 AEANRALAHYRW 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS7	NP_001260339.1	uS7_Mitochondria_Mammalian	21..216	CDD:271249	81/204 (40%)
MRPS7	NP_057055.2	uS7_Mitochondria_Mammalian	35..240	CDD:271249	81/204 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147739
Domainoid	1	1.000	134	1.000	Domainoid score	I5027
eggNOG	1	0.900	-	-		E1_COG0049
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9321
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4335
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45686
OrthoDB	1	1.010	-	-		D1212658at2759
OrthoFinder	1	1.000	-	-		FOG0003102
OrthoInspector	1	1.000	-	-		oto88669
orthoMCL	1	0.900	-	-		OOG6_102117
Panther	1	1.100	-	-	LDO	PTHR11205
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4022
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770