Protein Alignment Cdk1 and CKA2

DIOPT Version :10

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_014704.1
• Gene: CKA2 / 854227
• SGDID: S000005587
• Length: 339
• Species: Saccharomyces cerevisiae
• Alignment Length: 304
• Identity: 87/304 - (28%)
• Similarity: 159/304 - (52%)
• Gaps: 33/304 - (10%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQ---IVAMKKIRLESDDEGVPSTAIREISLLKELK-HE 61
            :.::|.|.|||.|.|..|:.||..:..|   |..:|.::::.        ..||:.:|..|. ..
Yeast    47 ISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKK--------IYRELKILTNLTGGP 103

  Fly    62 NIVCLEDVLME-ENRI-YLIFEFL-SMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRR 123
            |:|.|.|::.: :::| .||||.: ::|.:....:..:..      ::.|..|:..|:.:||...
Yeast   104 NVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPD------IQYYFTQLLIALDYCHSMG 162

  Fly   124 VLHRDLKPQNLLIDKS-GLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDI 187
            ::|||:||||::||.: ..:::.|:||. .|..|...|...:.:.:::.||:|:...:|...:|:
Yeast   163 IMHRDVKPQNVMIDPTERKLRLIDWGLA-EFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDL 226

  Fly   188 WSIGCIFAEMATRK-PLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSL---PDYKN-----TFPC 243
            ||:||:.|.:..:| |.|:|.|..|||.::..:|.|.....:.|...|   .:|.|     |...
Yeast   227 WSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMRDFTKKS 291

  Fly   244 WSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
            | |:.:|::.|......:|||..:|.||...|::||:.::|.:|
Yeast   292 W-THFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	86/300 (29%)
CKA2	NP_014704.1	STKc_CK2_alpha	30..335	CDD:271034	87/304 (29%)