DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk1 and CDC2

DIOPT Version :9

Sequence 1:	NP_476797.1	Gene:	Cdk1 / 34411	FlyBaseID:	FBgn0004106	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_566911.1	Gene:	CDC2 / 824036	AraportID:	AT3G48750	Length:	294	Species:	Arabidopsis thaliana

Alignment Length:	288	Identity:	185/288 - (64%)
Similarity:	232/288 - (80%)	Gaps:	2/288 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            |:.:||:|||||||||||||.|:::|.:.:|:||||||.:|||||||||||||||||::|.|||.
plant     1 MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHSNIVK 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |:||:..|.|:||:||:|.:||||:|||.| |...:..::::|||||...|.:||..||||||||
plant    66 LQDVVHSEKRLYLVFEYLDLDLKKHMDSTP-DFSKDLHMIKTYLYQILRGIAYCHSHRVLHRDLK 129

  Fly   131 PQNLLID-KSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIF 194
            ||||||| ::..:|:|||||.|:||||||.:|||:|||||||||:||||..||.||||||:||||
plant   130 PQNLLIDRRTNSLKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSHHYSTPVDIWSVGCIF 194

  Fly   195 AEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDAN 259
            |||.::||||.|||||||||::|||:.||.||.|.|||||||||:.||.|....|...:.|||.:
plant   195 AEMISQKPLFPGDSEIDQLFKIFRIMGTPYEDTWRGVTSLPDYKSAFPKWKPTDLETFVPNLDPD 259

  Fly   260 GIDLIQKMLIYDPVHRISAKDILEHPYF 287
            |:||:.|||:.||..||:|:..|||.||
plant   260 GVDLLSKMLLMDPTKRINARAALEHEYF 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	182/284 (64%)
CDC2	NP_566911.1	PLN00009	1..294	CDD:177649	185/288 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	389	1.000	Domainoid score	I149
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	392	1.000	Inparanoid score	I492
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	1	1.000	-	-		oto3887
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X960
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.730