Protein Alignment Cdk1 and cdk4

DIOPT Version :9

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001071245.1
• Gene: cdk4 / 777730
• ZFINID: ZDB-GENE-060929-974
• Length: 297
• Species: Danio rerio
• Alignment Length: 298
• Identity: 131/298 - (43%)
• Similarity: 191/298 - (64%)
• Gaps: 23/298 - (7%)

  Fly     4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELK---HENIVC 65
            :|.:.:||.|.||.|||.|:|.:||.||:|.:|::::.:|:|.:.:||::|||.|:   |.|||.
Zfish     9 YEPVAEIGGGAYGTVYKARDRDSGQFVALKSVRVQTNQDGLPLSTVREVALLKRLEQFDHPNIVR 73

  Fly    66 LEDVLM-----EENRIYLIFEFLSMDLKKYMD-----SLPVDKHMESELVRSYLYQITSAILFCH 120
            |.||..     :|.::.|:||.:..||:.|::     .|||||      :|..:.|:...:.|.|
Zfish    74 LMDVCATLRTDQETKVTLVFEHVDQDLRAYLEKVPAPGLPVDK------IRDLMQQLLCGLAFLH 132

  Fly   121 RRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPV 185
            ..|||||||||:|:|:...|.:|:|||||.|.:...:.: |..:||||||:|||||.| .|:.||
Zfish   133 TNRVLHRDLKPENILVTSRGQVKLADFGLARIYSCHMAL-TPVVVTLWYRSPEVLLQS-TYATPV 195

  Fly   186 DIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLT 250
            ||||.|||||||..|||||.||||.|||.::|.::..|.||.||...:|..:  .|...|...:|
Zfish   196 DIWSTGCIFAEMFRRKPLFCGDSEADQLGKIFAVIGLPAEDQWPTDVTLSHH--NFSPQSPRPIT 258

  Fly   251 NQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFN 288
            :.:.::...|.:|:.|||.:||:.||||.:.|:||:|:
Zfish   259 DCVPDITEKGAELLLKMLTFDPLKRISALNALDHPFFS 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	130/295 (44%)
cdk4	NP_001071245.1	STKc_CDK4	8..295	CDD:143368	130/295 (44%)
		S_TKc	9..295	CDD:214567	130/295 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810