Protein Alignment Cdk1 and cdkl5

DIOPT Version :10

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001139240.1
• Gene: cdkl5 / 559341
• ZFINID: ZDB-GENE-081022-110
• Length: 1080
• Species: Danio rerio
• Alignment Length: 305
• Identity: 115/305 - (37%)
• Similarity: 178/305 - (58%)
• Gaps: 27/305 - (8%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            |..||.:..:|||.||||.|.|::.|.::||:||.:...::|.|..|.:||:.:|:.||.:|||.
Zfish    10 MNKFEVLGIVGEGAYGVVLKCRHKETKELVAIKKFKDSEENEEVKETTLRELKMLRTLKQDNIVE 74

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLP----VDKHMESELVRSYLYQITSAILFCHRRRVLH 126
            |::......::||:||::..::.:.::.||    .||      ||||::|:..||.:||:..::|
Zfish    75 LKEAFRRRGKLYLVFEYVEKNMLELLEELPNGALPDK------VRSYIFQLIKAIHWCHKNEIVH 133

  Fly   127 RDLKPQNLLIDKSGLIKVADFGLGR--SFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWS 189
            ||:||:||||..:.::|:.|||..|  |.|.... ||..:.|.|||:||:|||:| |...||:||
Zfish   134 RDIKPENLLISANDILKLCDFGFARNLSEGSDAN-YTEYVATRWYRSPELLLGAP-YGKAVDMWS 196

  Fly   190 IGCIFAEMATRKPLFQGDSEIDQLFRMFRIL-KTPTEDIW-----PGVTSLPDYKNTFPCWSTNQ 248
            :|||..|::..:|||.|:|||||||.:.::| ..|.|.:.     |....|     .||..|..|
Zfish   197 VGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPPEQMKLFYSNPRFAGL-----RFPSVSHPQ 256

  Fly   249 LTNQLKNLDANG--IDLIQKMLIYDPVHRISAKDILEHPYFNGFQ 291
            ..::......||  :||::.:|..:|..|...:..|.||.|.|.:
Zfish   257 TLDRRYLGIINGLMLDLMKNLLCLNPTERFLTEQCLNHPVFQGLR 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	112/297 (38%)
cdkl5	NP_001139240.1	STKc_CDKL5	11..297	CDD:270838	112/298 (38%)