DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk1 and Cdk1

DIOPT Version :9

Sequence 1:	NP_476797.1	Gene:	Cdk1 / 34411	FlyBaseID:	FBgn0004106	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_062169.1	Gene:	Cdk1 / 54237	RGDID:	2319	Length:	297	Species:	Rattus norvegicus

Alignment Length:	288	Identity:	213/288 - (73%)
Similarity:	247/288 - (85%)	Gaps:	0/288 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            |||:.|||||||||||||||||:|.||||||||||||||::|||||||||||||||||:|.|||.
  Rat     1 MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVS 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |:||||:::|:||||||||||||||:||:|..:.|:|.||:||||||...|:|||.|||||||||
  Rat    66 LQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLK 130

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            |||||||..|.||:|||||.|:||||:|:||||:||||||:|||||||.|||.||||||||.|||
  Rat   131 PQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFA 195

  Fly   196 EMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANG 260
            |:||:||||.||||||||||:||.|.||..::||.|.||.|||||||.|....|.:.:||||.||
  Rat   196 ELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENG 260

  Fly   261 IDLIQKMLIYDPVHRISAKDILEHPYFN 288
            :||:.|||:|||..|||.|..|:||||:
  Rat   261 LDLLSKMLVYDPAKRISGKMALKHPYFD 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	209/283 (74%)
Cdk1	NP_062169.1	STKc_CDK1_euk	3..287	CDD:270845	209/283 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353082
Domainoid	1	1.000	440	1.000	Domainoid score	I528
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68203
Inparanoid	1	1.050	447	1.000	Inparanoid score	I1575
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	1	1.000	-	-		oto96018
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X960
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760