Protein Alignment Cdk1 and CDK18

DIOPT Version :9

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: XP_016856912.1
• Gene: CDK18 / 5129
• HGNCID: 8751
• Length: 572
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 140/292 - (47%)
• Similarity: 204/292 - (69%)
• Gaps: 12/292 - (4%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            :|.:.|::|:|||||..|:|||::||..:||:|:|||| .:||.|.|||||:||||.|||.|||.
Human   239 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKNLKHANIVT 302

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKH----MESELVRSYLYQITSAILFCHRRRVLH 126
            |.|::..:..:.|:||:|..|||:|:|      |    |....|:.:::|:...:.:||.|::||
Human   303 LHDLIHTDRSLTLVFEYLDSDLKQYLD------HCGNLMSMHNVKIFMFQLLRGLAYCHHRKILH 361

  Fly   127 RDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIG 191
            ||||||||||::.|.:|:|||||.|:..:|.:.|::|:||||||.|:|||||..||.|:|:|.:|
Human   362 RDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVG 426

  Fly   192 CIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKN-TFPCWSTNQLTNQLKN 255
            ||..||||.:|||.|.:..::|..:||:|.||||:.|||||:..:::. :|||:....|.|....
Human   427 CIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPR 491

  Fly   256 LDANGIDLIQKMLIYDPVHRISAKDILEHPYF 287
            ||.:||.|:..:|:|:...|:||:..|.|.||
Human   492 LDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	137/288 (48%)
CDK18	XP_016856912.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820