Protein Alignment Cdk1 and Cdk12

DIOPT Version :9

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001262167.1
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Alignment Length: 300
• Identity: 119/300 - (39%)
• Similarity: 180/300 - (60%)
• Gaps: 23/300 - (7%)

  Fly     4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLED 68
            ||.|.:|||||||.|||.|:..|..:||:||:|||.:.||.|.||:|||.:|::|.|.|||.|.:
  Fly   804 FEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHE 868

  Fly    69 VL----------MEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRR 123
            ::          .::...||:||::..||...::|..||.:.|:.  .|.:.|:...:.:||::.
  Fly   869 IVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENN--ASIMKQLLDGLNYCHKKN 931

  Fly   124 VLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIP--VRIYTHEIVTLWYRAPEVLLGSPRYSCPVD 186
            .||||:|..|:|::..|.:|:|||||.|.:...  .|.||::::|||||.||:|||..||...:|
  Fly   932 FLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSID 996

  Fly   187 IWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDY-----KNTFPCWST 246
            :||.|||..|:..::||||.::|:.||..:.:|..:|...:||.|..||.:     |.|    ..
  Fly   997 VWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKT----HR 1057

  Fly   247 NQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPY 286
            .:|....:.:.|..:||:.|||..||..||:|:|.|..|:
  Fly  1058 RRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPW 1097

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	119/299 (40%)
Cdk12	NP_001262167.1	STKc_CDK12	796..1098	CDD:270847	119/299 (40%)
		S_TKc	804..1098	CDD:214567	119/299 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442461
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940