Protein Alignment Cdk1 and Cdk12

DIOPT Version :10

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_649325.2
• Gene: Cdk12 / 40385
• FlyBaseID: FBgn0037093
• Length: 1157
• Species: Drosophila melanogaster
• Alignment Length: 300
• Identity: 119/300 - (39%)
• Similarity: 180/300 - (60%)
• Gaps: 23/300 - (7%)

  Fly     4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLED 68
            ||.|.:|||||||.|||.|:..|..:||:||:|||.:.||.|.||:|||.:|::|.|.|||.|.:
  Fly   804 FEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHE 868

  Fly    69 VL----------MEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRR 123
            ::          .::...||:||::..||...::|..||.:.|:.  .|.:.|:...:.:||::.
  Fly   869 IVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENN--ASIMKQLLDGLNYCHKKN 931

  Fly   124 VLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIP--VRIYTHEIVTLWYRAPEVLLGSPRYSCPVD 186
            .||||:|..|:|::..|.:|:|||||.|.:...  .|.||::::|||||.||:|||..||...:|
  Fly   932 FLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSID 996

  Fly   187 IWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDY-----KNTFPCWST 246
            :||.|||..|:..::||||.::|:.||..:.:|..:|...:||.|..||.:     |.|    ..
  Fly   997 VWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPAVWPNVIKLPLFHTLKQKKT----HR 1057

  Fly   247 NQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPY 286
            .:|....:.:.|..:||:.|||..||..||:|:|.|..|:
  Fly  1058 RRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPW 1097

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	119/299 (40%)
Cdk12	NP_649325.2	STKc_CDK12	796..1098	CDD:270847	119/299 (40%)