Protein Alignment Cdk1 and Cdk14

DIOPT Version :10

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001382511.1
• Gene: Cdk14 / 362316
• RGDID: 1305544
• Length: 469
• Species: Rattus norvegicus
• Alignment Length: 292
• Identity: 137/292 - (46%)
• Similarity: 197/292 - (67%)
• Gaps: 9/292 - (3%)

  Fly     2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCL 66
            :.:||:||:|||:|..||||::::.|::||:|.|||: ::||.|.|||||.||||.|||.|||.|
  Rat   133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHANIVLL 196

  Fly    67 EDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKP 131
            .|::..:..:.|:||::..||.:|||..|...|.::  |:.:|:|:...:.:.|:|.:|||||||
  Rat   197 HDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDN--VKLFLFQLLRGLSYIHQRYILHRDLKP 259

  Fly   132 QNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAE 196
            |||||..:|.:|:|||||.|:..:|...|::|:||||||.|:|||||..||..:|:|.:||||.|
  Rat   260 QNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVE 324

  Fly   197 MATRKPLFQGDSEI-DQLFRMFRILKTPTEDIWPGVTSLPDYK-NTFPCWSTNQLT---NQLKNL 256
            |......|.|..:| |||.|:|.:|.||.||.||||.|||.:| ..|..:|:..|.   |:|..:
  Rat   325 MIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTVYSSKSLRQAWNKLSYV 389

  Fly   257 DANGIDLIQKMLIYDPVHRISAKDILEHPYFN 288
            : :..||..|:|...|.:|:||:..|.|.||:
  Rat   390 N-HAEDLASKLLQCSPKNRLSAQAALSHEYFS 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	135/288 (47%)
Cdk14	NP_001382511.1	STKc_PFTAIRE1	129..431	CDD:143374	137/292 (47%)