DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk1 and Cdk14

DIOPT Version :9

Sequence 1:	NP_476797.1	Gene:	Cdk1 / 34411	FlyBaseID:	FBgn0004106	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_001382511.1	Gene:	Cdk14 / 362316	RGDID:	1305544	Length:	469	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	137/292 - (46%)
Similarity:	197/292 - (67%)	Gaps:	9/292 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCL 66
            :.:||:||:|||:|..||||::::.|::||:|.|||: ::||.|.|||||.||||.|||.|||.|
  Rat   133 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHANIVLL 196

  Fly    67 EDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKP 131
            .|::..:..:.|:||::..||.:|||..|...|.::  |:.:|:|:...:.:.|:|.:|||||||
  Rat   197 HDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDN--VKLFLFQLLRGLSYIHQRYILHRDLKP 259

  Fly   132 QNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAE 196
            |||||..:|.:|:|||||.|:..:|...|::|:||||||.|:|||||..||..:|:|.:||||.|
  Rat   260 QNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVE 324

  Fly   197 MATRKPLFQGDSEI-DQLFRMFRILKTPTEDIWPGVTSLPDYK-NTFPCWSTNQLT---NQLKNL 256
            |......|.|..:| |||.|:|.:|.||.||.||||.|||.:| ..|..:|:..|.   |:|..:
  Rat   325 MIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTVYSSKSLRQAWNKLSYV 389

  Fly   257 DANGIDLIQKMLIYDPVHRISAKDILEHPYFN 288
            : :..||..|:|...|.:|:||:..|.|.||:
  Rat   390 N-HAEDLASKLLQCSPKNRLSAQAALSHEYFS 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	135/288 (47%)
Cdk14	NP_001382511.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920