Protein Alignment Cdk1 and CDKL4

DIOPT Version :9

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001333840.1
• Gene: CDKL4 / 344387
• HGNCID: 19287
• Length: 379
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 111/305 - (36%)
• Similarity: 179/305 - (58%)
• Gaps: 19/305 - (6%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            ||.:||:.|.|||:||||:|.||:.:||:||:||.....||..|...|:|||.:||:|||.|:|.
Human     1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPNLVN 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |.:|...:.:::|:||:....|...::..|  ..:...:::|.|:|...|:.|||....:|||:|
Human    66 LIEVFRRKRKMHLVFEYCDHTLLNELERNP--NGVADGVIKSVLWQTLQALNFCHIHNCIHRDIK 128

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            |:|:||.|.|:||:.|||..:.. ||...||..:.|.||||||:|:|..:|...||||:|||:||
Human   129 PENILITKQGIIKICDFGFAQIL-IPGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFA 192

  Fly   196 EMATRKPLFQGDSEIDQLFRMFRILKT---------PTEDIWPGVTSLPDYKNTFPCWSTNQLTN 251
            |:.|.:||:.|.|::|||:.:.|.|..         .:...:.|: |:|:.::      ...|..
Human   193 ELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGI-SIPEPED------METLEE 250

  Fly   252 QLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGLVR 296
            :..::....::.::..|..:|..|::...:||..||:.||...::
Human   251 KFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDSFQEAQIK 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	105/292 (36%)
CDKL4	NP_001333840.1	[NKR]KIAxRE	45..51		1/5 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910