DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdk1 and Cdk16

DIOPT Version :9

Sequence 1:	NP_476797.1	Gene:	Cdk1 / 34411	FlyBaseID:	FBgn0004106	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_035179.1	Gene:	Cdk16 / 18555	MGIID:	97516	Length:	496	Species:	Mus musculus

Alignment Length:	288	Identity:	141/288 - (48%)
Similarity:	208/288 - (72%)	Gaps:	4/288 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            :|.:.|::|:|||||..||||:::||..:||:|:|||| .:||.|.|||||:||||:|||.|||.
Mouse   162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKHANIVT 225

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |.|::..|..:.|:||:|..|||:|:|......:|.:  |:.:|:|:...:.:|||::|||||||
Mouse   226 LHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNVINMHN--VKLFLFQLLRGLAYCHRQKVLHRDLK 288

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            ||||||::.|.:|:|||||.|:..||.:.|::|:||||||.|::||||..||..:|:|.:||||.
Mouse   289 PQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFY 353

  Fly   196 EMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKN-TFPCWSTNQLTNQLKNLDAN 259
            ||||.:|||.|.:..:||..:||||.||||:.|||:.|..:::. .:|.:....|.:....||::
Mouse   354 EMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFRTYNYPKYRAEALLSHAPRLDSD 418

  Fly   260 GIDLIQKMLIYDPVHRISAKDILEHPYF 287
            |.||:.|:|.::..:||||:|..:||:|
Mouse   419 GADLLTKLLQFEGRNRISAEDARKHPFF 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	139/284 (49%)
Cdk16	NP_035179.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..95
Cdk16	NP_035179.1	STKc_PCTAIRE1	162..458	CDD:270854	141/288 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820