Protein Alignment Cdk1 and cdk-5

DIOPT Version :9

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_499783.1
• Gene: cdk-5 / 176774
• WormBaseID: WBGene00000407
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 289
• Identity: 148/289 - (51%)
• Similarity: 211/289 - (73%)
• Gaps: 5/289 - (1%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            |.:::|:|||||||||.|:|.||:.:|:|||:|::||:.|||||||:|:|||.:|:||||.|:|.
 Worm     1 MLNYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVR 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |.||:..||::.|:||:...||||:.|||  :.:|:::..||.:.|:...:.|||...|||||||
 Worm    66 LYDVVHSENKLTLVFEYCDQDLKKFFDSL--NGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLK 128

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            ||||||:.:|.:|:|||||.|:||:|||.::.|:||||||.|:||.|:..|:..:|:||.|||||
 Worm   129 PQNLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFA 193

  Fly   196 EMATR-KPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQL-KNLDA 258
            |::.. :|||.|....|||.|:|:.|.:|:||.||.:|.||||| .:|.:......:|: .||::
 Worm   194 EISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYK-PYPIYHPTLTWSQIVPNLNS 257

  Fly   259 NGIDLIQKMLIYDPVHRISAKDILEHPYF 287
            .|.||:||:|:.:|..||.|...|.|.||
 Worm   258 RGRDLLQKLLVCNPAGRIDADAALRHAYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	145/285 (51%)
cdk-5	NP_499783.1	PLN00009	1..292	CDD:177649	148/289 (51%)
		STKc_CDK5	3..286	CDD:143344	145/285 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850