Protein Alignment Cdk1 and cdk-5

DIOPT Version :10

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_499783.1
• Gene: cdk-5 / 176774
• WormBaseID: WBGene00000407
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 289
• Identity: 148/289 - (51%)
• Similarity: 211/289 - (73%)
• Gaps: 5/289 - (1%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            |.:::|:|||||||||.|:|.||:.:|:|||:|::||:.|||||||:|:|||.:|:||||.|:|.
 Worm     1 MLNYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVR 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |.||:..||::.|:||:...||||:.|||  :.:|:::..||.:.|:...:.|||...|||||||
 Worm    66 LYDVVHSENKLTLVFEYCDQDLKKFFDSL--NGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLK 128

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            ||||||:.:|.:|:|||||.|:||:|||.::.|:||||||.|:||.|:..|:..:|:||.|||||
 Worm   129 PQNLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFA 193

  Fly   196 EMATR-KPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQL-KNLDA 258
            |::.. :|||.|....|||.|:|:.|.:|:||.||.:|.||||| .:|.:......:|: .||::
 Worm   194 EISNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYK-PYPIYHPTLTWSQIVPNLNS 257

  Fly   259 NGIDLIQKMLIYDPVHRISAKDILEHPYF 287
            .|.||:||:|:.:|..||.|...|.|.||
 Worm   258 RGRDLLQKLLVCNPAGRIDADAALRHAYF 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	145/285 (51%)
cdk-5	NP_499783.1	STKc_CDK5	3..286	CDD:143344	145/285 (51%)