Protein Alignment Cdk1 and cdk-2

DIOPT Version :10

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001021537.2
• Gene: cdk-2 / 171911
• WormBaseID: WBGene00019362
• Length: 338
• Species: Caenorhabditis elegans
• Alignment Length: 301
• Identity: 146/301 - (48%)
• Similarity: 208/301 - (69%)
• Gaps: 14/301 - (4%)

  Fly     4 FEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLED 68
            |..:.:|||||||||:|..:.......|:|.||.:.|:||:|||.:||||.:|:|:|:|||.|.|
 Worm    15 FCSLRRIGEGTYGVVFKAIHVRDNVKCALKMIRTDRDEEGIPSTCLREISCIKDLQHDNIVTLFD 79

  Fly    69 VLMEENRIYLIFEFLSMDLKKYMDSL-PVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQ 132
            ::...:::|::|||:..|||..::.| |.:..:....|:|:::|:.||:.:||.||::|||||||
 Worm    80 IIYANSKLYMVFEFIDRDLKNLLEMLEPTNSVLPPNYVKSFMWQLLSALSYCHLRRIVHRDLKPQ 144

  Fly   133 NLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEM 197
            |:|:..||:||:|||||.|:|..|.|.||||:||||||.||:||||.|||..:|:||:||||:|:
 Worm   145 NILVSDSGVIKIADFGLARNFSFPSRNYTHEVVTLWYRPPEILLGSQRYSTSLDMWSLGCIFSEI 209

  Fly   198 ATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLD----- 257
            |:.||||.|:.||.|||::|.|:.||....||||.|.|.||..||.|..|     ||.|:
 Worm   210 ASNKPLFPGECEISQLFKIFEIVGTPNIKSWPGVDSFPHYKAVFPQWPVN-----LKKLEETSCL 269

  Fly   258 -ANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGLVRN 297
             .||:|:::::|.|.|..|::||..|.|.||  .|:|..:|
 Worm   270 TGNGLDVLREILRYPPERRLTAKGALSHRYF--LQNGFTQN 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	141/289 (49%)
cdk-2	NP_001021537.2	STKc_CDK_like	15..300	CDD:270823	141/289 (49%)