DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdk1 and Cdk5

DIOPT Version :9

Sequence 1:NP_476797.1 Gene:Cdk1 / 34411 FlyBaseID:FBgn0004106 Length:297 Species:Drosophila melanogaster
Sequence 2:NP_543161.1 Gene:Cdk5 / 140908 RGDID:70514 Length:292 Species:Rattus norvegicus


Alignment Length:292 Identity:166/292 - (56%)
Similarity:221/292 - (75%) Gaps:5/292 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            |:.:||:|||||||||.|:|.:||.|.:|||:|::||:.|||||||:|:|||.|||||||:|||.
  Rat     1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVR 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |.|||..:.::.|:|||...|||||.||...|  ::.|:|:|.|:|:...:.|||.|.|||||||
  Rat    66 LHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGD--LDPEIVKSLLFQLLKGLGFCHSRNVLHRDLK 128

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            ||||||:::|.:|:|||||.|:||||||.|:.|:||||||.|:||.|:..||..:|:||.|||||
  Rat   129 PQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFA 193

  Fly   196 EMATR-KPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCW-STNQLTNQLKNLDA 258
            |:|.. :|||.|:...|||.|:||:|.||||:.||.:|.||||| .:|.: :|..|.|.:..|:|
  Rat   194 ELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYK-PYPMYPATTSLVNVVPKLNA 257

  Fly   259 NGIDLIQKMLIYDPVHRISAKDILEHPYFNGF 290
            .|.||:|.:|..:||.||||::.|:||||:.|
  Rat   258 TGRDLLQNLLKCNPVQRISAEEALQHPYFSDF 289

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdk1NP_476797.1 STKc_CDK1_euk 3..287 CDD:270845 162/285 (57%)
Cdk5NP_543161.1 STKc_CDK5 3..286 CDD:143344 162/285 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1010560at2759
OrthoFinder 1 1.000 - - FOG0000411
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100334
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.820

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