Protein Alignment Cdk1 and Cdk5

DIOPT Version :10

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_031694.1
• Gene: Cdk5 / 12568
• MGIID: 101765
• Length: 292
• Species: Mus musculus
• Alignment Length: 292
• Identity: 166/292 - (56%)
• Similarity: 222/292 - (76%)
• Gaps: 5/292 - (1%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            |:.:||:|||||||||.|:|.:||.|.:|||:|::||:.|||||||:|:|||.|||||||:|||.
Mouse     1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVR 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |.|||..:.::.|:|||...|||||.||...|  ::.|:|:|:|:|:...:.|||.|.|||||||
Mouse    66 LHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGD--LDPEIVKSFLFQLLKGLGFCHSRNVLHRDLK 128

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            ||||||:::|.:|:|||||.|:||||||.|:.|:||||||.|:||.|:..||..:|:||.|||||
Mouse   129 PQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFA 193

  Fly   196 EMATR-KPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCW-STNQLTNQLKNLDA 258
            |:|.. :|||.|:...|||.|:||:|.||||:.||.:|.||||| .:|.: :|..|.|.:..|:|
Mouse   194 ELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYK-PYPMYPATTSLVNVVPKLNA 257

  Fly   259 NGIDLIQKMLIYDPVHRISAKDILEHPYFNGF 290
            .|.||:|.:|..:||.||||::.|:||||:.|
Mouse   258 TGRDLLQNLLKCNPVQRISAEEALQHPYFSDF 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	162/285 (57%)
Cdk5	NP_031694.1	STKc_CDK5	3..286	CDD:143344	162/285 (57%)