Protein Alignment Cdk1 and CDK3

DIOPT Version :9

• Sequence 1: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Sequence 2: NP_001249.1
• Gene: CDK3 / 1018
• HGNCID: 1772
• Length: 305
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 189/288 - (65%)
• Similarity: 229/288 - (79%)
• Gaps: 1/288 - (0%)

  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65
            |:.|:|:|||||||||||||.:||.|||:||:|||||:.:.|||||||||||||||||||.|||.
Human     1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVR 65

  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLK 130
            |.||:..|.::||:|||||.||||||||.| ...:...|::|||:|:...:.|||..||:|||||
Human    66 LLDVVHNERKLYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLK 129

  Fly   131 PQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFA 195
            ||||||::.|.||:|||||.|:||:|:|.||||:|||||||||:||||..|:..|||||||||||
Human   130 PQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFA 194

  Fly   196 EMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANG 260
            ||.|||.||.||||||||||:||:|.||:||.|||||.|||||.:||.|:...|...:.||:..|
Human   195 EMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPEG 259

  Fly   261 IDLIQKMLIYDPVHRISAKDILEHPYFN 288
            .||:.::|.|||..||:||..|.||||:
Human   260 RDLLMQLLQYDPSQRITAKTALAHPYFS 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	186/283 (66%)
CDK3	NP_001249.1	PLN00009	1..293	CDD:177649	189/288 (66%)
		STKc_CDK2_3	3..286	CDD:270844	186/283 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X960
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.720