DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5096 and slit3

DIOPT Version :9

Sequence 1:NP_723576.1 Gene:CG5096 / 34410 FlyBaseID:FBgn0032235 Length:491 Species:Drosophila melanogaster
Sequence 2:NP_001072738.1 Gene:slit3 / 780195 XenbaseID:XB-GENE-991050 Length:1519 Species:Xenopus tropicalis


Alignment Length:636 Identity:128/636 - (20%)
Similarity:209/636 - (32%) Gaps:232/636 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 LTKSATLAAAIFCIVLSQVSG------QTKD---ETTTTETPKEKIKVIDSKLC-KKCNCYIDTN 57
            |.:..|:....||:....:.|      |.||   ..|.:|.|......:.   | ..|.|  ..|
 Frog   226 LRQRKTIGQFTFCMSPVHLRGFNVADVQKKDFVCPGTQSEPPSCNANAVS---CPSACTC--SNN 285

  Fly    58 LLDCSEKLQDWLSAEDWEDLTNGNVVFKTINLEHNNLTSVP---ILPKYDVENLYLANNQIDSIS 119
            ::||..|....:.|    :|..|.:   .|.||.|::.::|   ..|...::.:.::.|||..|:
 Frog   286 VVDCRGKGLTEIPA----NLPEGII---EIRLEQNSIKAIPAGVFTPYKKLKRIDISKNQISEIA 343

  Fly   120 VGAFQNLTELVTLDLSHNRLTSKVLVPDVFKGPF-------------------TVQDFESLENLK 165
            ..||..|..|.:|.|..|::|      ::.||.|                   .|..|:.|:||.
 Frog   344 ADAFSGLKSLTSLVLYGNKIT------EIPKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLN 402

  Fly   166 TLNLGYNDLHSLDADLFEHIPHIEELVLCSNSFHVID--------------------------QL 204
            .|:|..|.|.::...||..:..|:.|.|..|.| |.|                          :|
 Frog   403 LLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPF-VCDCHLKWLADYLQDNPIETSGARCTSPRRL 466

  Fly   205 SETAISGLQSLK--------------------------------ILDVSYMEIDDLPDTILHGPR 237
            :...||.::|.|                                |:|.|..:|..:|..:.....
 Frog   467 ANKRISQIKSKKFRCTGSEDYRSKFSGDCFMDLVCPEKCRCEGTIVDCSNQKISRIPSYLPEYTS 531

  Fly   238 DLEI------FIAAGNLFNQLPKALKY-----------------ATNLTSLVLNENPIENL---- 275
            ||.:      .:.|..:|.:||...|.                 |..:..|:|..|.:|::    
 Frog   532 DLRLNDNEITVLEATGIFKKLPNLRKINLSNNKIKDIREGAFDGAAGVQELMLTGNQLESVHGRM 596

  Fly   276 -------------------IGDNVFPPLTKLTHLSMTFMSKLYKIGPGAFSELQSLTELILSDNK 321
                               |.::.|..|:.:..||: :.:::..|.||||:.|.||:.:.|..|.
 Frog   597 FRGLVGLKTLMLRSNLMSCINNDTFTGLSSVRLLSL-YDNRITTITPGAFNTLVSLSTINLLSNP 660

  Fly   322 L-----LNEIDEEALSKNVTGGQ-------YLDYPPLEKVYL----------------------- 351
            .     |..:.:....|.|..|.       :|...|::.|.:                       
 Frog   661 FNCNCHLAWLGKWLRKKRVVSGNPRCQKPYFLKEIPIQDVAIQDFTCDGNEESSCLPASHCPEQC 725

  Fly   352 ---------NNCNVSTLPK-------ELLVRWDKLKALDLRFNPWNCDESNDFLINVLIDRINKT 400
                     .|..:.||||       ||.:..:.|.::.        .|.:.|....|||..|.:
 Frog   726 TCVESVVRCGNQGLRTLPKNIPKDVTELYLEGNHLTSVP--------KEISSFKHLTLIDLSNNS 782

  Fly   401 TPVLA-----------------KDVKCGGPNKLNDVTLLRVANEHMIESST 434
            ..||:                 ..::|...:..|.:..|||...|..:.||
 Frog   783 ISVLSNYTFSNVTQLSTLILSYNRLRCIPVHAFNGLKSLRVLTLHGNDIST 833

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5096NP_723576.1 LRR_RI 69..378 CDD:238064 94/485 (19%)
leucine-rich repeat 85..104 CDD:275380 6/21 (29%)
LRR_8 105..174 CDD:290566 23/87 (26%)
leucine-rich repeat 105..128 CDD:275380 7/22 (32%)
leucine-rich repeat 129..163 CDD:275380 11/52 (21%)
LRR_8 163..222 CDD:290566 22/116 (19%)
leucine-rich repeat 164..187 CDD:275380 7/22 (32%)
leucine-rich repeat 188..214 CDD:275380 10/51 (20%)
leucine-rich repeat 215..238 CDD:275380 6/54 (11%)
leucine-rich repeat 239..261 CDD:275380 7/44 (16%)
LRR_8 260..322 CDD:290566 19/84 (23%)
leucine-rich repeat 262..286 CDD:275380 7/46 (15%)
leucine-rich repeat 287..311 CDD:275380 8/23 (35%)
leucine-rich repeat 346..369 CDD:275380 8/61 (13%)
leucine-rich repeat 370..388 CDD:275380 2/17 (12%)
slit3NP_001072738.1 LRRNT 29..60 CDD:214470
LRR_8 57..117 CDD:290566
LRR_4 60..97 CDD:289563
leucine-rich repeat 60..82 CDD:275380
LRR_RI <83..216 CDD:238064
leucine-rich repeat 83..106 CDD:275380
LRR_8 105..165 CDD:290566
leucine-rich repeat 107..130 CDD:275380
leucine-rich repeat 131..154 CDD:275380
LRR_8 155..213 CDD:290566
leucine-rich repeat 155..178 CDD:275380
leucine-rich repeat 179..202 CDD:275380
leucine-rich repeat 203..305 CDD:275380 20/87 (23%)
TPKR_C2 211..260 CDD:301599 8/33 (24%)
LRRNT 276..307 CDD:214470 10/39 (26%)
LRR_8 307..363 CDD:290566 17/55 (31%)
leucine-rich repeat 307..328 CDD:275380 6/20 (30%)
LRR_4 327..367 CDD:289563 12/45 (27%)
leucine-rich repeat 329..352 CDD:275380 7/22 (32%)
LRR_8 351..435 CDD:290566 23/89 (26%)
leucine-rich repeat 353..373 CDD:275380 8/25 (32%)
leucine-rich repeat 377..400 CDD:275380 3/22 (14%)
leucine-rich repeat 401..422 CDD:275380 7/20 (35%)
leucine-rich repeat 425..516 CDD:275380 14/91 (15%)
TPKR_C2 433..>463 CDD:301599 4/30 (13%)
LRRNT 501..531 CDD:214470 5/29 (17%)
LRR_4 533..570 CDD:289563 6/36 (17%)
leucine-rich repeat 533..554 CDD:275380 4/20 (20%)
LRR_8 553..613 CDD:290566 7/59 (12%)
leucine-rich repeat 555..578 CDD:275380 2/22 (9%)
leucine-rich repeat 579..602 CDD:275380 4/22 (18%)
LRR_8 602..661 CDD:290566 15/59 (25%)
leucine-rich repeat 603..626 CDD:275380 3/22 (14%)
leucine-rich repeat 627..650 CDD:275380 8/23 (35%)
leucine-rich repeat 651..741 CDD:275380 11/89 (12%)
LRRCT 659..708 CDD:214507 8/48 (17%)
LRRNT 720..752 CDD:214470 5/31 (16%)
leucine-rich repeat 742..772 CDD:275380 8/37 (22%)
LRR_8 771..831 CDD:290566 12/59 (20%)
leucine-rich repeat 773..796 CDD:275380 6/22 (27%)
LRR_4 795..836 CDD:289563 8/39 (21%)
leucine-rich repeat 797..820 CDD:275380 2/22 (9%)
leucine-rich repeat 821..842 CDD:275380 6/13 (46%)
LRRCT 853..902 CDD:214507
EGF 916..947 CDD:278437
EGF_CA 952..989 CDD:238011
EGF_CA 994..1027 CDD:238011
EGF_CA 1031..1068 CDD:238011
EGF_CA 1070..1106 CDD:238011
LamG 1155..1308 CDD:238058
GHB_like 1454..1517 CDD:304424
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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