Protein Alignment CG5096 and Slitrk5

DIOPT Version :10

• Sequence 1: NP_723576.1
• Gene: CG5096 / 34410
• FlyBaseID: FBgn0032235
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_001365697.1
• Gene: Slitrk5 / 75409
• MGIID: 2679448
• Length: 982
• Species: Mus musculus
• Alignment Length: 755
• Identity: 150/755 - (19%)
• Similarity: 240/755 - (31%)
• Gaps: 334/755 - (44%)

  Fly     8 TLAAAIFCIVLSQVSGQTKDETTTTETPKEKIKVID--SKLC-KKCNCYIDTNLLDCSEKLQDWL 69
            |||.|:..:|||           ..||       ||  .::| ..|.|.....:|..|.:.:..:
Mouse    50 TLAFAVTSLVLS-----------CAET-------IDYYGEICDNACPCEEKDGILTVSCENRGII 96

  Fly    70 SAED--------WEDLTNGNVVFKTINLEHNNLTSVPILPKYDVENLYLANNQIDSISVGAFQNL 126
            |..:        :..|.:||::.:....|..|.|...|        |:|.:|.|..|..|||..|
Mouse    97 SLSEISPPRFPIYHLLLSGNLLSRLYPNEFVNYTGASI--------LHLGSNVIQDIETGAFHGL 153

  Fly   127 TELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGYN-----------DLHSLD-- 178
            ..|..|.|::|:|  ::|..|.|.|         ||||:.|.:.||           .||.|.
Mouse   154 RGLRRLHLNNNKL--ELLRDDTFLG---------LENLEYLQVDYNYISVIEPNAFGKLHMLQVL 207

  Fly   179 -----------------------------------ADLFEHIPHIEELVLCSNSFHV-------- 200
                                               ..|.:|:..:.||.|..|.::.
Mouse   208 ILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLK 272

  Fly   201 --IDQLSETAISG---------LQSLKILDVSYME------IDDL---PDTIL------------ 233
              :|.:|.:|:.|         |....:.:||..|      |.|.   |.|.|
Mouse   273 DWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRKLISDYEMRPQTPLSTTGYLHTTPAS 337

  Fly   234 ---------------------------------------------HGPR---------------- 237
                                                         :||.
Mouse   338 VNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPLECPTA 402

  Fly   238 ---DLEIFIAAGNL-----------------FNQLPKAL----KY-----------ATNLTSLVL 267
               :|:|.....|:                 :|  ||.:    .|           ||.|..|.|
Mouse   403 CTCNLQISDLGLNVNCQERKIESIAELQPKPYN--PKKMYLTENYITVVRRTDFLEATGLDLLHL 465

  Fly   268 NENPIENLIGDNVFPPLTKLTHLSMTFMSKLYKIGPGAFSELQSLTELILSDNKLLNEIDEEALS 332
            ..|.| ::|.|..|..|..|..|.:. .:::.::.|..|..||||..|.|..|          |.
Mouse   466 GNNRI-SMIQDRAFGDLGNLRRLYLN-GNRIERLSPELFYGLQSLQYLFLQYN----------LI 518

  Fly   333 KNVTGGQYLDYPPLEKVYLNNCNVSTLPKEL-----LVR----------------WDKLKAL--- 373
            :.:..|.:...|.|:.::|||..:..:|..:     |:|                .|:|.:|
Mouse   519 REIQAGTFDPVPNLQLLFLNNNQLQAMPSGVFSGLTLLRLNLRGNSFTSLPVSGVLDQLTSLIQI 583

  Fly   374 DLRFNPWNCDESNDFL-INVLIDRINKTTPVLAKDVKCGGPNKLNDVTLLRVANEHMIE------ 431
            ||..|||:|  :.|.: :.:.|:::.  ..||..:|.|..|.|..:..:..:.:|.:..
Mouse   584 DLHDNPWDC--TCDVVGMKLWIEQLK--VGVLVDEVICKAPKKFAETYMRSIKSELLCPDYSDVV 644

  Fly   432 ------------------------SSTG----------------SLIWVGLLVVLLIAVPTIIGA 456
                                    :|||                |::.:.||:|.:::|....|.
Mouse   645 VSTPTPSSIQVPSRTNAATPAVRLNSTGTPAGLGAGTGASSVPLSVLILSLLLVFIMSVFVAAGL 709

  Fly   457 Y--VMKRRGCFGVFRRHDSGASSALYNR---TSFNEDFHI 491
            :  |||||      :::.|..:|.  |.   :|||..:.:
Mouse   710 FVLVMKRR------KKNQSDHTST--NNSDVSSFNMQYSV 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR	54..>322	CDD:443914	88/459 (19%)
		leucine-rich repeat	85..104	CDD:275380	4/18 (22%)
		leucine-rich repeat	105..128	CDD:275380	9/22 (41%)
		leucine-rich repeat	129..163	CDD:275380	10/33 (30%)
		leucine-rich repeat	164..187	CDD:275380	9/70 (13%)
		leucine-rich repeat	188..214	CDD:275380	9/44 (20%)
		leucine-rich repeat	215..238	CDD:275380	10/107 (9%)
		leucine-rich repeat	239..261	CDD:275380	8/53 (15%)
		leucine-rich repeat	262..286	CDD:275380	9/23 (39%)
		leucine-rich repeat	287..311	CDD:275380	5/23 (22%)
		leucine-rich repeat	346..369	CDD:275380	7/43 (16%)
		leucine-rich repeat	370..388	CDD:275380	8/20 (40%)
Slitrk5	NP_001365697.1	leucine-rich repeat	87..104	CDD:275380	2/16 (13%)
		leucine-rich repeat	108..131	CDD:275380	5/22 (23%)
		LRR	<111..>260	CDD:443914	40/167 (24%)
		leucine-rich repeat	132..155	CDD:275380	10/30 (33%)
		leucine-rich repeat	156..179	CDD:275380	10/33 (30%)
		leucine-rich repeat	180..203	CDD:275380	5/22 (23%)
		leucine-rich repeat	204..225	CDD:275380	1/20 (5%)
		leucine-rich repeat	227..251	CDD:275380	2/23 (9%)
		LRRCT	260..>298	CDD:214507	6/37 (16%)
		PPP1R42	416..>588	CDD:455733	41/185 (22%)
		LRR_8	458..518	CDD:404697	21/71 (30%)
		leucine-rich repeat	460..483	CDD:275380	9/23 (39%)
		leucine-rich repeat	484..507	CDD:275380	5/23 (22%)
		leucine-rich repeat	508..553	CDD:275380	12/54 (22%)
		leucine-rich repeat	555..579	CDD:275380	4/23 (17%)
		LRRCT	588..>624	CDD:214507	12/39 (31%)