Protein Alignment CG5096 and lrrn1

DIOPT Version :10

• Sequence 1: NP_723576.1
• Gene: CG5096 / 34410
• FlyBaseID: FBgn0032235
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_001124166.1
• Gene: lrrn1 / 568527
• ZFINID: ZDB-GENE-071126-1
• Length: 717
• Species: Danio rerio
• Alignment Length: 417
• Identity: 106/417 - (25%)
• Similarity: 181/417 - (43%)
• Gaps: 75/417 - (17%)

  Fly    16 IVLSQVSGQTKDETTTTETPKEKIKVIDSKLCKKCNC-----------YIDTNLLDCSE----KL 65
            |:|..|.|.:  ...:||.|            :.|.|           |.:...:||::    ::
Zfish    17 ILLLAVLGLS--SVHSTECP------------QLCVCEIRPWFTPQSTYREATTVDCNDLHLTRI 67

  Fly    66 QDWLSAEDWEDLTNGNVVFKT------------INLEHNNLTS---VPILPKYDVENLYLANNQI 115
            ...|||:....|...|.:.:|            ::|..||.::   :.:.....:..|:|..|||
Zfish    68 PGNLSADTQVLLLQSNYIARTSEELEQLLNLTELDLSQNNFSNIRDIGLTNMSQLTTLHLEENQI 132

  Fly   116 DSISVGAFQNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGYNDLHSLDAD 180
            ..:...:.|:||.|..|.::||:::|  :.|:.|.|         |.||..|:|..|.|.::|:.
Zfish   133 VEMPDFSLQDLTNLQELYINHNQISS--IAPNAFAG---------LRNLLRLHLNSNRLKAIDSR 186

  Fly   181 LFEHIPHIEELVLCSNSFHVIDQLSETAISGLQSLKILDVSYMEIDDLPDTILHGPRDLEIFIAA 245
            .||..|::|.|::..|....|..|:...::.|:||.:   :.||:.|:|.....|..:||.....
Zfish   187 WFESTPNLEILMIGENPVVGILDLNFKPLTNLRSLVL---AGMELTDIPGNAFVGLDNLESLSFY 248

  Fly   246 GNLFNQLPK-ALKYATNLTSLVLNENPIENLIGDNVFPPLTKLTHLSMTFMSKLYKIGPGAFSEL 309
            .|...::|: ||:...||..|.||:|||.. |.:..|..:.:|..|.:..|.:|..|...|...|
Zfish   249 DNKLVRVPQTALQKLPNLKFLDLNKNPIHK-IQEGDFKNMLRLKELGINNMGELVSIDRFALDNL 312

  Fly   310 QSLTELILSDNKLLNEIDEEALSKNVTGGQYLDYPPLEKVYLNNCNVSTLPKELLVRWDKLKALD 374
            ..||:|..::|...:.:...|         :.|.|.||.:.|||..:::|.:........|:.:.
Zfish   313 PELTKLEATNNPKFSYVSRLA---------FRDLPALESLMLNNNALNSLYQATADSLPNLREIS 368

  Fly   375 LRFNPWNCDESNDFLINVLIDRINKTT 401
            :..||..||....::.:      ||||
Zfish   369 IHSNPLRCDCVIQWMSS------NKTT 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR	54..>322	CDD:443914	78/287 (27%)
		leucine-rich repeat	85..104	CDD:275380	4/33 (12%)
		leucine-rich repeat	105..128	CDD:275380	7/22 (32%)
		leucine-rich repeat	129..163	CDD:275380	9/33 (27%)
		leucine-rich repeat	164..187	CDD:275380	8/22 (36%)
		leucine-rich repeat	188..214	CDD:275380	6/25 (24%)
		leucine-rich repeat	215..238	CDD:275380	6/22 (27%)
		leucine-rich repeat	239..261	CDD:275380	6/22 (27%)
		leucine-rich repeat	262..286	CDD:275380	9/23 (39%)
		leucine-rich repeat	287..311	CDD:275380	7/23 (30%)
		leucine-rich repeat	346..369	CDD:275380	6/22 (27%)
		leucine-rich repeat	370..388	CDD:275380	5/17 (29%)
lrrn1	NP_001124166.1	leucine-rich repeat	55..74	CDD:275380	4/18 (22%)
		LRR	<73..375	CDD:443914	86/325 (26%)
		leucine-rich repeat	98..121	CDD:275380	3/22 (14%)
		leucine-rich repeat	122..145	CDD:275380	7/22 (32%)
		leucine-rich repeat	146..169	CDD:275380	9/33 (27%)
		leucine-rich repeat	170..193	CDD:275380	8/22 (36%)
		leucine-rich repeat	194..217	CDD:275380	5/22 (23%)
		leucine-rich repeat	218..241	CDD:275380	8/25 (32%)
		leucine-rich repeat	242..265	CDD:275380	6/22 (27%)
		leucine-rich repeat	266..289	CDD:275380	9/23 (39%)
		leucine-rich repeat	290..314	CDD:275380	7/23 (30%)
		leucine-rich repeat	315..337	CDD:275380	5/30 (17%)
		leucine-rich repeat	340..353	CDD:275378	5/12 (42%)
		leucine-rich repeat	364..376	CDD:275378	3/11 (27%)
		LRRCT	372..414	CDD:214507	8/24 (33%)
		Ig	430..510	CDD:472250
		Ig strand B	444..448	CDD:409353
		Ig strand C	457..461	CDD:409353
		Ig strand E	483..487	CDD:409353
		Ig strand F	497..502	CDD:409353
		Ig strand G	510..513	CDD:409353
		FN3	532..601	CDD:214495