DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5096 and zgc:153913

DIOPT Version :9

Sequence 1:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001073448.1	Gene:	zgc:153913 / 559700	ZFINID:	ZDB-GENE-061103-397	Length:	496	Species:	Danio rerio

Alignment Length:	426	Identity:	109/426 - (25%)
Similarity:	165/426 - (38%)	Gaps:	63/426 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 CNCYIDTNLLDCSEKLQDWLSAEDWEDLTNGNVVFKTI-NLEHNNLTSVPILPKYDVENLYLANN 113
            |.|:..:.|: ||:.....|.......:....||...| :|:..:......|.|     |...|.
Zfish    25 CQCFSGSKLV-CSDDRMKSLPVNISTQVRELIVVASGIPDLDQQSFPETLRLSK-----LVFLNG 83

  Fly   114 QIDSISVGAFQNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENLKTLNLGYNDLHSLD 178
            .:.|:|..||:.|.||..|::|.|          :......:|.|.||.||..|.|..|.|..:|
Zfish    84 MLKSVSGEAFERLVELRELEISGN----------ICWMSLDIQTFSSLTNLTRLLLNNNKLSGVD 138

  Fly   179 ADLFEHIPHIEELVLCSN---------------------SFHVIDQLSETAISGLQSLKILDVSY 222
            |.||..:..:|.|.|..|                     ||:.|..||.........|::|.:..
Zfish   139 AGLFHSLHQLEMLQLRGNGLSFLSGRLFQRLHRLQELDLSFNQISSLSTELFQNNSELRVLSLQA 203

  Fly   223 MEIDDLPDTILHGPRDLEIFIAAGNLFNQLPKALKYATNLTSLVLNENPIENLIGDNVFPPLTKL 287
            .:|.:|||.|......|:......||...|... .:..:|.:|:|.:|.:|.|. :.||..|..:
Zfish   204 NKIPNLPDGIFTHLDHLQELNLRSNLIRVLTPG-SFPASLKTLILKKNLLEKLT-NAVFHTLHYI 266

  Fly   288 THLSMTFMSKLYKIGPGAFSELQSLTELILSDNKL----------LNEIDEEALSKN----VTGG 338
            |:|.:: .:.|.::....|..|.||..|.||:|::          |..|....|.||    |...
Zfish   267 TYLDLS-QNSLTEVPADLFQNLISLETLDLSENRISTLAGSVFKGLFSIKSVYLQKNSLISVDAH 330

  Fly   339 QYLDYPPLEKVYLNNCNVSTLPKELLVRWDKLKALDLRFNPWNCDESNDFLINVLIDRINKTTPV 403
            ...|...|:.:.|:|.::.::|.......|.....:||.|||:||....:..:.|     |....
Zfish   331 LLKDQHDLQLLDLSNNSLRSIPSGFFEDLDFQCVFELRGNPWSCDCGIHYFYDWL-----KYNHK 390

  Fly   404 LAKD---VKCGGPNKLNDVTLLRVANEHMIESSTGS 436
            ..||   |.|..|..:....|..|..|.::.|...|
Zfish   391 HVKDLSRVSCEAPELIQGHNLRSVDREQLVCSRNSS 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	87/344 (25%)
		leucine-rich repeat	85..104	CDD:275380	4/19 (21%)
		LRR_8	105..174	CDD:290566	21/68 (31%)
		leucine-rich repeat	105..128	CDD:275380	7/22 (32%)
		leucine-rich repeat	129..163	CDD:275380	8/33 (24%)
		LRR_8	163..222	CDD:290566	21/79 (27%)
		leucine-rich repeat	164..187	CDD:275380	9/22 (41%)
		leucine-rich repeat	188..214	CDD:275380	9/46 (20%)
		leucine-rich repeat	215..238	CDD:275380	7/22 (32%)
		leucine-rich repeat	239..261	CDD:275380	4/21 (19%)
		LRR_8	260..322	CDD:290566	20/61 (33%)
		leucine-rich repeat	262..286	CDD:275380	9/23 (39%)
		leucine-rich repeat	287..311	CDD:275380	5/23 (22%)
		leucine-rich repeat	346..369	CDD:275380	4/22 (18%)
		leucine-rich repeat	370..388	CDD:275380	7/17 (41%)
zgc:153913	NP_001073448.1	leucine-rich repeat	75..98	CDD:275380	9/27 (33%)
		LRR_RI	141..>350	CDD:238064	52/211 (25%)
		LRR_8	147..206	CDD:290566	11/58 (19%)
		leucine-rich repeat	148..171	CDD:275380	4/22 (18%)
		leucine-rich repeat	172..195	CDD:275380	5/22 (23%)
		LRR_8	194..252	CDD:290566	15/58 (26%)
		leucine-rich repeat	196..219	CDD:275380	7/22 (32%)
		leucine-rich repeat	220..241	CDD:275380	4/21 (19%)
		leucine-rich repeat	242..265	CDD:275380	9/23 (39%)
		leucine-rich repeat	266..289	CDD:275380	5/23 (22%)
		LRR_8	267..324	CDD:290566	16/57 (28%)
		leucine-rich repeat	290..313	CDD:275380	6/22 (27%)
		leucine-rich repeat	314..337	CDD:275380	6/22 (27%)
		leucine-rich repeat	338..359	CDD:275380	4/20 (20%)
		TPKR_C2	370..>404	CDD:301599	11/38 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3266
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910