DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5096 and caps

DIOPT Version :9

Sequence 1:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001303391.1	Gene:	caps / 39493	FlyBaseID:	FBgn0023095	Length:	811	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	129/485 - (26%)
Similarity:	203/485 - (41%)	Gaps:	93/485 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KIKVIDSKLCKKCNCYIDTNLLDCSEKLQDWLSAEDWEDLTNGNVVFKTINLEHNNLTSV---PI 99
            |:|.|||.:    ..|.....||.|  ..|.|:..:.....:..:  :.::|:||.:..|   ..
  Fly    83 KLKTIDSSM----QFYAQLTFLDLS--FNDMLTIPERSFAYHAKL--QELHLDHNKIGQVSNKTF 139

  Fly   100 LPKYDVENLYLANNQIDSISVGAFQNLTELVTLDLSHNRLTSKVLVPDVFKGPFTVQDFESLENL 164
            |....:..|.|..|.|..:....|..:.:|..|:|..||::.  :.|....|         |:||
  Fly   140 LGLSTISVLNLRGNLIAELEYRTFSPMVKLAELNLGQNRISH--IDPHALDG---------LDNL 193

  Fly   165 KTLNLGYNDLHSLDADL-FEHIPHIEELVLCSNSFHVI---------------------DQLSET 207
            :.|.|..|.|.::..:| |:.:..:.||.|.:|||..|                     ..:|..
  Fly   194 RVLYLDDNTLTTVPGELTFQALHSLAELYLGTNSFMTIPGGAFQDLKGLTRLDLRGAGLHNISGD 258

  Fly   208 AISGLQSLKILDVSYMEIDDLPDTILHGPRDLEIFIAAGNLFNQLPKALKYATNLTSLVLNENPI 272
            |:.||.||:.||:|...:..:|..                .|.:|.:       |..|.:.:|..
  Fly   259 ALKGLVSLRFLDLSDNRLPAIPTA----------------AFQRLGR-------LEQLNIGQNDF 300

  Fly   273 ENLIGDNVFPPLTKLTHLSMTFMSKLYKIGPGAFSELQSLTELILSDNKLLNEIDEEALSKNVTG 337
            | :|....|..|.:|.||.:|...:|.::..||||...:|..|.||.||.|||:...||     |
  Fly   301 E-VISSGAFSGLRELRHLELTGAQRLRRVESGAFSGNTNLEHLNLSSNKQLNELSSIAL-----G 359

  Fly   338 GQYLDYPPLEKVYLNNCNVSTLPKELLVRWDKLKALDLRFNPWNCDESNDFLINVLIDR--INKT 400
            |    .|.|..|.|....:|:| .|.||.|..|:.|||..||:.||....:|.::|:.|  ..:.
  Fly   360 G----LPHLSTVVLKANQLSSL-DEGLVPWADLQTLDLSENPFECDCRLLWLRHLLVSRNASGQY 419

  Fly   401 TPVLAKDVKCGGPNKLNDVTLLRVANEHMIESSTGSL---IWVGLLVVLLIAVPTIIG--AYVMK 460
            .||:     |..|..|.|:.|..:| |.::..:.|:.   ..:|:|||...|:.|.:.  .|..:
  Fly   420 APVI-----CAYPTALRDLPLAHLA-EPLLGCAHGAASKQAIIGILVVACAALITTLALVLYTCR 478

  Fly   461 RRGCFGVFRRHDS-GASSALYNRTSFNEDF 489
            .| ...:.:.|.: |.....|.:|..:|::
  Fly   479 HR-IREMLKGHSALGRKEREYQKTFSDEEY 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	89/333 (27%)
		leucine-rich repeat	85..104	CDD:275380	5/21 (24%)
		LRR_8	105..174	CDD:290566	18/68 (26%)
		leucine-rich repeat	105..128	CDD:275380	5/22 (23%)
		leucine-rich repeat	129..163	CDD:275380	8/33 (24%)
		LRR_8	163..222	CDD:290566	23/80 (29%)
		leucine-rich repeat	164..187	CDD:275380	7/23 (30%)
		leucine-rich repeat	188..214	CDD:275380	11/46 (24%)
		leucine-rich repeat	215..238	CDD:275380	5/22 (23%)
		leucine-rich repeat	239..261	CDD:275380	2/21 (10%)
		LRR_8	260..322	CDD:290566	21/61 (34%)
		leucine-rich repeat	262..286	CDD:275380	7/23 (30%)
		leucine-rich repeat	287..311	CDD:275380	9/23 (39%)
		leucine-rich repeat	346..369	CDD:275380	9/22 (41%)
		leucine-rich repeat	370..388	CDD:275380	8/17 (47%)
caps	NP_001303391.1	leucine-rich repeat	75..96	CDD:275380	6/16 (38%)
		LRR_8	96..155	CDD:290566	13/62 (21%)
		leucine-rich repeat	97..120	CDD:275380	5/24 (21%)
		leucine-rich repeat	121..144	CDD:275380	5/24 (21%)
		LRR_8	143..201	CDD:290566	17/68 (25%)
		leucine-rich repeat	145..168	CDD:275380	5/22 (23%)
		LRR_RI	147..397	CDD:238064	84/294 (29%)
		leucine-rich repeat	169..192	CDD:275380	8/33 (24%)
		leucine-rich repeat	193..217	CDD:275380	7/23 (30%)
		LRR_8	217..276	CDD:290566	16/58 (28%)
		leucine-rich repeat	218..241	CDD:275380	7/22 (32%)
		leucine-rich repeat	242..265	CDD:275380	4/22 (18%)
		LRR_8	265..321	CDD:290566	18/79 (23%)
		leucine-rich repeat	266..289	CDD:275380	7/38 (18%)
		leucine-rich repeat	290..313	CDD:275380	7/23 (30%)
		LRR_8	312..374	CDD:290566	26/70 (37%)
		leucine-rich repeat	314..335	CDD:275380	8/20 (40%)
		leucine-rich repeat	339..363	CDD:275380	13/32 (41%)
		LRRCT	395..445	CDD:214507	16/55 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45617
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010